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1. (WO2018002849) TRITERPENOID INHIBITORS OF HUMAN IMMUNODEFICIENCY VIRUS REPLICATION
Latest bibliographic data on file with the International Bureau    Submit observation

Pub. No.: WO/2018/002849 International Application No.: PCT/IB2017/053880
Publication Date: 04.01.2018 International Filing Date: 28.06.2017
IPC:
C07J 63/00 (2006.01) ,A61K 31/56 (2006.01) ,A61P 31/18 (2006.01)
Applicants: VIIV HEALTHCARE UK (NO.5) LIMITED[GB/GB]; 980 Great West Road Brentford, Middlesex TW8 9GS, GB
Inventors: VENABLES, Brian Lee; US
SWIDORSKI, Jacob; US
SIN, Ny; US
REGUEIRO-REN, Alicia; US
Priority Data:
62/356,84030.06.2016US
Title (EN) TRITERPENOID INHIBITORS OF HUMAN IMMUNODEFICIENCY VIRUS REPLICATION
(FR) INHIBITEURS TRITERPÉNOÏDES DE LA RÉPLICATION DU VIRUS DE L'IMMUNODÉFICIENCE HUMAINE
Abstract: front page image
(EN) Compounds having drug and bio-affecting properties, their pharmaceutical compositions and methods of use are set forth. In particular, triterpenoid compounds that possess unique antiviral activity are provided as HIV maturation inhibitors, as represented by compounds of Formula (I). These compounds are useful for the treatment of HIV and AIDS.
(FR) La présente invention concerne des composés ayant des propriétés thérapeutiques et bioactives, leurs compositions pharmaceutiques et leurs procédés d'utilisation. L'invention concerne, en particulier, des composés triterpénoïdes qui possèdent une activité antivirale unique, utilisés comme inhibiteurs de maturation du VIH, tels que représentés par des composés de formule (I). Ces composés s'avèrent utiles dans le traitement du VIH et du SIDA.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)