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1. (WO2018002153) HYCANTHONE DERIVATIVES AND PRIMAQUINE DERIVATIVES FOR USE IN THE PREVENTION AND/OR THE TREATMENT OF DISORDERS ASSOCIATED TO GAMMAHERPESVIRUS

Pub. No.:    WO/2018/002153    International Application No.:    PCT/EP2017/066020
Publication Date: Fri Jan 05 00:59:59 CET 2018 International Filing Date: Thu Jun 29 01:59:59 CEST 2017
IPC: A61K 31/352
A61K 31/382
A61K 31/4706
A61K 45/06
A61P 31/12
A61P 31/22
Applicants: ASSISTANCE PUBLIQUE - HOPITAUX DE PARIS
INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM)
UNIVERSITE PIERRE ET MARIE CURIE (PARIS 6)
UNIVERSITE PARIS DESCARTES
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS)
Inventors: DUPIN, Nicolas
MARCELIN, Anne-Geneviève
CALVEZ, Vincent
GRANGE, Philippe
Title: HYCANTHONE DERIVATIVES AND PRIMAQUINE DERIVATIVES FOR USE IN THE PREVENTION AND/OR THE TREATMENT OF DISORDERS ASSOCIATED TO GAMMAHERPESVIRUS
Abstract:
The present invention relates to compounds of the following general formula (I) or (II) or a pharmaceutically acceptable salt and/or solvate thereof, for use in the prevention and/or the treatment of disorders associated to gammaherpesvirinae, in particular to the human herpesvirus 8 (HHV8) or the human herpes virus 4 (HHV4), and pharmaceutical compositions containing such compounds.