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1. (WO2018002115) VORTIOXETINE DOSING REGIMES FOR FAST ONSET OF ANTIDEPRESSANT EFFECT
Latest bibliographic data on file with the International Bureau    Submit observation

Pub. No.:    WO/2018/002115    International Application No.:    PCT/EP2017/065958
Publication Date: 04.01.2018 International Filing Date: 28.06.2017
IPC:
A61K 31/495 (2006.01), A61P 25/24 (2006.01)
Applicants: H. LUNDBECK A/S [DK/DK]; Ottiliavej 9 2500 Valby (DK)
Inventors: MORILLO, Connie, Sanchez; (DK).
SØBY, Karina, Krøjer; (DK).
BANG-ANDERSEN, Benny; (DK)
Priority Data:
62/357722 01.07.2016 US
Title (EN) VORTIOXETINE DOSING REGIMES FOR FAST ONSET OF ANTIDEPRESSANT EFFECT
(FR) SCHÉMAS POSOLOGIQUES DE LA VORTIOXÉTINE DESTINÉS À UNE APPARITION RAPIDE DE L'EFFET ANTIDÉPRESSEUR
Abstract: front page image
(EN)A dose regimen comprising the simultaneous administration of two pharmaceutical compositions, wherein the first pharmaceutical composition is a composition comprising vortioxetine or a pharmaceutically acceptable salt thereof for once daily oral administration, and the second pharmaceutical composition is a composition comprising vortioxetine or a pharmaceutically acceptable salt thereof which together with said first composition quickly achieves a steady-state plasma level of vortioxetine in said patient which steady-state plasma level is the same as the steady-state vortioxetine plasma level achieved by the administration to said patient of said first composition alone.
(FR)L'invention concerne un schéma posologique comprenant l'administration simultanée de deux compositions pharmaceutiques, la première composition pharmaceutique étant une composition comprenant de la vortioxétine ou un sel de qualité pharmaceutique de cette dernière, pour une administration quotidienne unique par voie orale, et la seconde composition pharmaceutique étant une composition comprenant de la vortioxétine ou un sel de qualité pharmaceutique de cette dernière, qui, associée à ladite première composition, permet d'atteindre rapidement une concentration plasmatique stable de vortioxétine chez ledit patient, ladite concentration plasmatique stable étant identique à la concentration plasmatique stable de vortioxétine obtenue par l'administration audit patient de ladite première composition seule.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)