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1. (WO2018002081) HCMV ENTRY INHIBITORS
Latest bibliographic data on file with the International Bureau    Submit observation

Pub. No.:    WO/2018/002081    International Application No.:    PCT/EP2017/065902
Publication Date: 04.01.2018 International Filing Date: 27.06.2017
IPC:
A61K 39/00 (2006.01), A61K 38/00 (2006.01), C07K 14/71 (2006.01), C12N 15/113 (2010.01)
Applicants: AICURIS ANTI-INFECTIVE CURES GMBH [DE/DE]; Friedrich-Ebert-Str. 475 42117 Wuppertal (DE)
Inventors: SINZGER, Christian; (DE).
LAIB SAMPAIO, Kerstin; (DE).
STEGMANN, Cora; (DE).
ADLER, Barbara; (DE)
Agent: KILGER, Ute; BOEHMERT & BOEHMERT Hollerallee 32 28209 Bremen (DE)
Priority Data:
16176520.1 27.06.2016 EP
Title (EN) HCMV ENTRY INHIBITORS
(FR) INHIBITEURS D'ENTRÉE DE HCMV.
Abstract: front page image
(EN)Subject matter of the present invention is a soluble PDGFR-alpha-Fc chimera or a PDGFR- alpha derived peptide or an anti- PDGFR-alpha antibody or a PDGFR-alpha antibody fragment or anti- PDGFR-alpha non-Ig scaffold for inhibiting HCMV entry for use in a method of treatment in a subject that has been infected by HCMV or for use in a method of prophylaxis of HCMV infection in a subject that has not yet been infected by HCMV.
(FR)L'invention porte sur une chimère soluble de PDGFR-alpha-Fc, un peptide dérivé de PDGFR-alpha, un anticorps anti-PDGFR-alpha, un fragment d'anticorps de PDGFR-alpha ou un échafaudage non Ig anti-PDGFR-alpha pour inhiber l'entrée du HCMV pour l'utiliser dans le traitement chez un sujet infecté par le CMVH, ou dans un but de prophylaxie d'une infection par le CMVH chez un sujet qui n'a pas encore été infecté.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)