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1. (WO2018002081) HCMV ENTRY INHIBITORS

Pub. No.:    WO/2018/002081    International Application No.:    PCT/EP2017/065902
Publication Date: Fri Jan 05 00:59:59 CET 2018 International Filing Date: Wed Jun 28 01:59:59 CEST 2017
IPC: A61K 39/00
A61K 38/00
C07K 14/71
C12N 15/113
Applicants: AICURIS ANTI-INFECTIVE CURES GMBH
Inventors: SINZGER, Christian
LAIB SAMPAIO, Kerstin
STEGMANN, Cora
ADLER, Barbara
Title: HCMV ENTRY INHIBITORS
Abstract:
Subject matter of the present invention is a soluble PDGFR-alpha-Fc chimera or a PDGFR- alpha derived peptide or an anti- PDGFR-alpha antibody or a PDGFR-alpha antibody fragment or anti- PDGFR-alpha non-Ig scaffold for inhibiting HCMV entry for use in a method of treatment in a subject that has been infected by HCMV or for use in a method of prophylaxis of HCMV infection in a subject that has not yet been infected by HCMV.