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1. (WO2018002079) PHARMACEUTICAL COMPOSITION COMPRISING FLUORINE-18 LABELLED GASES
Latest bibliographic data on file with the International BureauSubmit observation

Pub. No.: WO/2018/002079 International Application No.: PCT/EP2017/065900
Publication Date: 04.01.2018 International Filing Date: 27.06.2017
IPC:
A61K 51/04 (2006.01) ,A61K 51/12 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
51
Preparations containing radioactive substances for use in therapy or testing in vivo
02
characterised by the carrier
04
Organic compounds
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
51
Preparations containing radioactive substances for use in therapy or testing in vivo
12
characterised by a special physical form, e.g. emulsion, microcapsules, liposomes
Applicants:
ASOCIACIÓN CENTRO DE INVESTIGACIÓN COOPERATIVA EN BIOMATERIALES - CIC BIOMAGUNE [ES/ES]; Parque Científico y Tecnológico de Gipuzkoa Paseo Miramón, 182, Edificio Empresarial C 20009 SAN SEBASTIÁN, ES
Inventors:
LLOP ROIG, Jordi; ES
GÓMEZ VALLEJO, Vanessa; ES
REESE, Torsten; ES
LECUONA FERNÁNDEZ, Aitor; ES
Agent:
ZBM PATENTS - ZEA, BARLOCCI & MARKVARDSEN; Pl. Catalunya, 1 2nd floor 08002 BARCELONA, ES
Priority Data:
16382304.028.06.2016EP
Title (EN) PHARMACEUTICAL COMPOSITION COMPRISING FLUORINE-18 LABELLED GASES
(FR) COMPOSITION PHARMACEUTIQUE COMPRENANT DES GAZ MARQUÉS AU FLUOR-18
Abstract:
(EN) There is provided a process for the preparation of a pharmaceutical composition comprising an 18F-labelled gas selected from the group consisting of 18F-labelled sulphur hexafluoride ([18F]SF6) and 18F-labelled carbon tetrafluoride ([18F]CF4), comprising the steps: a) Filling a target with a gas mixture comprising a fluorinated gas selected from the group consisting of sulphur hexafluoride (SF6) and carbon tetrafluoride (CF4); b) Irradiating the gas mixture of step a) with protons with energies from 0.1 to 50 MeV. The pharmaceutical composition obtainable by the process and its uses in diagnosis, prognosis and lung function studies based on positron emission tomography (PET) are also claimed.
(FR) L'invention concerne un procédé de préparation d'une composition pharmaceutique comprenant 18F-gaz marqué sélectionné du groupe constitué de 18F- hexafluorure de soufre marqué([18F]SF6) et 18F-tétrafluorure de carbone marqué([18F]CF4), comprenant les étapes consistant à : a) remplir une cible avec un mélange gazeux comprenant un gaz fluoré sélectionné du groupe constitué de l'hexafluorure de soufre(SF6) et du tétrafluorure de carbone(CF4); b) irradiation du mélange gazeux de l'étape a) avec des protons ayant des énergies de 0,1 à 50 MeV. L'invention porte également sur la composition pharmaceutique pouvant être obtenue par le procédé et sur ses utilisations dans le diagnostic, le pronostic et l’étude de la fonction pulmonaire basée sur une tomographie par émission de positons (PET).
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)
Also published as:
EP3474902