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1. (WO2018001932) DEVICE, SYSTEM AND METHOD FOR DETECTING AN ANALYTE IN A BODY FLUID SAMPLE CONTAINING A PLURALITY OF CELLS
Latest bibliographic data on file with the International Bureau    Submit observation

Pub. No.:    WO/2018/001932    International Application No.:    PCT/EP2017/065648
Publication Date: 04.01.2018 International Filing Date: 26.06.2017
IPC:
G01N 33/543 (2006.01), G01N 33/574 (2006.01), G01N 33/74 (2006.01)
Applicants: KONINKLIJKE PHILIPS N.V. [NL/NL]; High Tech Campus 5 5656 AE Eindhoven (NL)
Inventors: VAN ROOSMALEN, Markus, Hendrikus; (NL).
NIEUWENHUIS, Jeroen, Hans; (NL).
VENGE, Per; (NL)
Agent: CLAVEAU, Olivier; (NL).
DE HAAN, Poul, Erik; (NL)
Priority Data:
16177241.3 30.06.2016 EP
16200668.8 25.11.2016 EP
Title (EN) DEVICE, SYSTEM AND METHOD FOR DETECTING AN ANALYTE IN A BODY FLUID SAMPLE CONTAINING A PLURALITY OF CELLS
(FR) DISPOSITIF, SYSTÈME ET PROCÉDÉ DE DÉTECTION D'ANALYTE DANS UN ÉCHANTILLON DE FLUIDE CORPOREL COMPRENANT UNE PLURALITÉ DE CELLULES
Abstract: front page image
(EN)The present invention relates to a device (100) for detecting an analyte (12) in a body fluid sample (14) containing a plurality of cells (16). The device (100) comprises a sample input (18) for receiving a body fluid sample (14) containing a plurality of cells (16), and an immunoassay unit (20) comprising a detection surface (28) for performing an immunoassay of said body fluid sample (14) containing a plurality of cells (16). The immunoassay unit (20) comprises an activating reagent (22) for activating the plurality of cells (16) contained in the body fluid sample (14) to release an analyte (12), an anti-analyte- antibody (24) capable of binding to said analyte (12) to form a complex (26) comprising said anti-analyte-antibody (24) and said analyte (12), wherein the forming of said complex (26) proceeds at least partially simultaneous to the activating of said plurality of cells (16).
(FR)La présente invention concerne un dispositif (100) de détection d'un analyte (12) dans un échantillon de fluide corporel (14) comprenant une pluralité de cellules (16). Le dispositif (100) comporte une entrée d'échantillon (18) pour recevoir un échantillon de fluide corporel (14) comprenant une pluralité de cellules (16), et une unité d'immuno-essai (20) comportant une surface de détection (28) pour effectuer un immuno-essai dudit échantillon de fluide corporel (14) comprenant une pluralité de cellules (16). L'unité d'immuno-essai (20) comporte un réactif d'activation (22) pour activer la pluralité de cellules (16) comprises dans l'échantillon de fluide corporel (14) en vue de libérer un analyte (12), un anticorps anti-analyte (24) apte à se lier audit analyte (12) en vue de former un complexe (26) comportant ledit anticorps anti-analyte (24) et ledit analyte (12), la formation dudit complexe (26) étant au moins partiellement simultanée à l'activation de ladite pluralité de cellules (16).
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)