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1. WO2017207430 - IMIDAZOLONE COMPOUNDS AS HUMAN NEUTROPHIL ELASTASE INHIBITORS

Publication Number WO/2017/207430
Publication Date 07.12.2017
International Application No. PCT/EP2017/062754
International Filing Date 26.05.2017
IPC
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
D
HETEROCYCLIC COMPOUNDS
403
Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/167
02
containing two hetero rings
04
directly linked by a ring-member-to-ring- member bond
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
D
HETEROCYCLIC COMPOUNDS
413
Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
14
containing three or more hetero rings
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
D
HETEROCYCLIC COMPOUNDS
403
Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/167
14
containing three or more hetero rings
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
D
HETEROCYCLIC COMPOUNDS
417
Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/196
14
containing three or more hetero rings
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
33
Heterocyclic compounds
395
having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
41
having five-membered rings with two or more ring hetero atoms, at least one of which is nitrogen, e.g. tetrazole
4164
1,3-Diazoles
4178
not condensed and containing further heterocyclic rings, e.g. pilocarpine, nitrofurantoin
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
11
Drugs for disorders of the respiratory system
C07D 403/04 (2006.01)
C07D 413/14 (2006.01)
C07D 403/14 (2006.01)
C07D 417/14 (2006.01)
A61K 31/4178 (2006.01)
A61P 11/00 (2006.01)
CPC
A61K 31/4178
A61K 31/4439
C07C 309/29
C07D 401/14
C07D 403/04
C07D 403/14
Applicants
  • CHIESI FARMACEUTICI S.P.A. [IT/IT]; Via Palermo, 26/A 43122 PARMA, IT
Inventors
  • SUTTON, Jonathan Mark; IT
  • HEALD, Robert Andrew; IT
  • JENNINGS, Andrew Stephen Robert; IT
  • CAPALDI, Carmelida; IT
  • ARMANI, Elisabetta; IT
Agents
  • MINOJA, Fabrizio; IT
Priority Data
16172196.431.05.2016EP
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) IMIDAZOLONE COMPOUNDS AS HUMAN NEUTROPHIL ELASTASE INHIBITORS
(FR) COMPOSÉS D'IMIDAZOLONE UTILISÉS EN TANT QU'INHIBITEURS DE L'ÉLASTASE NEUTROPHILE HUMAINE
Abstract
(EN)
This invention relates to imidazolone derivatives having human neutrophil elastase inhibitory properties, and their use in therapy.
(FR)
L'invention concerne des dérivés d'imidazolone présentant des propriétés inhibitrices de l'élastase neutrophile humaine, et leur utilisation thérapeutique.
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