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1. (WO2017205746) METHODS OF DIFFERENTIATING STEM CELL-DERIVED PROPRIOCEPTORS
Latest bibliographic data on file with the International Bureau    Submit observation

Pub. No.:    WO/2017/205746    International Application No.:    PCT/US2017/034690
Publication Date: 30.11.2017 International Filing Date: 26.05.2017
IPC:
C12N 5/079 (2010.01), C12N 5/0793 (2010.01), C12N 5/0797 (2010.01)
Applicants: MEMORIAL SLOAN-KETTERING CANCER CENTER [US/US]; 1275 York Avenue New York, NY 10065 (US)
Inventors: STUDER, Lorenz; (US).
ZELTNER, Nadja; (US)
Agent: HAN, Yi; (US).
KOLE, Lisa, B.; (US)
Priority Data:
62/342,370 27.05.2016 US
Title (EN) METHODS OF DIFFERENTIATING STEM CELL-DERIVED PROPRIOCEPTORS
(FR) PROCÉDÉS DE DIFFÉRENCIATION DE PROPRIOCEPTEURS DÉRIVÉS DES CELLULES SOUCHES
Abstract: front page image
(EN)The presently disclosed subject matter provides for in vitro methods of inducing differentiation of stem cells (e.g., human stem cells) into proprioceptors, proprioceptors generated by such methods, and compositions comprising such proprioceptors. The presently disclosed subject matter also provides for uses of such proprioceptors for preventing and/or treating disorders of proprioceptor neurons and/or neurodegenerative disorders (e.g., Friedreich's Ataxia).
(FR)La présente invention concerne des procédés in vitro d'induction de la différenciation de cellules souches (par exemple, des cellules souches humaines) en propriocepteurs, les propriocepteurs générés au moyen de tels procédés, et des compositions comprenant de tels propriocepteurs. Le sujet de la présente invention concerne également les utilisations de tels propriocepteurs servant à la prévention et/ou au traitement de troubles des neurones propriocepteurs et/ou des troubles de neurodégénérescence (par exemple, l'ataxie de Friedreich).
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)