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1. (WO2017205741) BIOANALYTICAL METHOD FOR THE CHARACTERIZATION OF SITE-SPECIFIC ANTIBODY-DRUG CONJUGATES
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Pub. No.: WO/2017/205741 International Application No.: PCT/US2017/034680
Publication Date: 30.11.2017 International Filing Date: 26.05.2017
IPC:
G01N 33/68 (2006.01)
G PHYSICS
01
MEASURING; TESTING
N
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33
Investigating or analysing materials by specific methods not covered by groups G01N1/-G01N31/131
48
Biological material, e.g. blood, urine; Haemocytometers
50
Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
68
involving proteins, peptides or amino acids
Applicants:
GENENTECH, INC. [US/US]; 1 DNA Way South San Francisco, California 94080, US (AE, AG, AM, AO, AU, AZ, BA, BB, BF, BH, BJ, BN, BR, BW, BY, BZ, CA, CF, CG, CI, CL, CM, CO, CR, CU, DJ, DM, DO, DZ, EC, EG, GA, GD, GE, GH, GM, GN, GQ, GT, GW, HN, ID, IL, IR, JP, KE, KG, KH, KM, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LY, MA, MD, ME, MG, ML, MN, MR, MW, MX, MY, MZ, NA, NE, NG, NI, NZ, OM, PA, PE, PG, PH, QA, RU, RW, SA, SC, SD, SG, SL, SN, ST, SV, SY, SZ, TD, TG, TH, TJ, TM, TN, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW)
F. HOFFMANN-LA ROCHE AG [CH/CH]; Grenzacherstrasse 124 4070 Basel, CH (AL, AT, BE, BG, CH, CN, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IN, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
Inventors:
SU, Dian; US
DARWISH, Martine; US
XU, Keyang; US
KAUR, Surinder; US
Agent:
ANDRUS, Alex; US
ACKERMAN, Lily J.; US
AUSENHUS, Scott L.; US
BERENDT, Frank JN; US
BUCKWALTER, Brian L.; US
CHANG, Y. Elaine; US
CHI, I. Shannon; US
COBURN, Cara M.; US
COULTER, Kathryn L.; US
CRISSEY, Todd M.; US
DAVIS, Jennifer L.; US
DUFFIELD, Jonathan J.; US
FANG, Carol A.; US
GHOSE, Shameek; US
HALL, Robert C.; US
HEIDER, Julie A.; US
HOLMES, Jennifer K.; US
JOHNSTON, Sean A.; US
KAFKA, Mark D.; US
KALE, Tamara A.; US
KALINOWSKI, Grant E.; US
KUBINEC, Jeffrey S.; US
LEE, Wendy M.; US
LI, Qianru; US
MARSCHANG, Diane L.; US
MARTINEAU, Janet M.; US
MCCLELLAN, Kelly B.; US
NESBITT, James E.; US
PASQUALONE, Danielle M.; US
PAZDERA, R. Minako; US
PENG, Tony W.; US
RICHARDSON, Jessica L.; US
ROPP, Traci H.; US
SCHWARTZ, Timothy R.; US
SHERMAN, Daniel E.; US
SHIN, Elinor K.; US
TAN, Anna M.; US
WAIS, Rebecca J.; US
YEUNG, Bonny G.; US
YONKER, Stephanie A.; US
Priority Data:
62/342,82527.05.2016US
Title (EN) BIOANALYTICAL METHOD FOR THE CHARACTERIZATION OF SITE-SPECIFIC ANTIBODY-DRUG CONJUGATES
(FR) PROCÉDÉ BIOANALYTIQUE POUR LA CARACTÉRISATION DE CONJUGUÉS ANTICORPS-MÉDICAMENT SPÉCIFIQUES D'UN SITE
Abstract:
(EN) Methods to rapidly and accurately detect, characterize, measure, and quantify site-specific antibody drug conjugates, that may be present in pre-clinical animal biological samples, or human biological samples, including plasma/serum and tissue samples.
(FR) L'invention porte sur des procédés pour détecter, caractériser, mesurer et quantifier précisément des conjugués anticorps-médicament spécifiques d'un site, pouvant être présents dans des échantillons biologiques animaux précliniques, ou dans des échantillons biologiques humains, y compris des échantillons de plasma/sérum et de tissu.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)