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1. (WO2017205663) SYSTEMS AND METHODS TO REPAIR TISSUE DEFECTS

Pub. No.:    WO/2017/205663    International Application No.:    PCT/US2017/034539
Publication Date: Fri Dec 01 00:59:59 CET 2017 International Filing Date: Fri May 26 01:59:59 CEST 2017
IPC: A61B 90/00
A61M 5/20
A61B 1/00
Applicants: SCRIPPS HEALTH
Inventors: D'LIMA, Darryl
COLWELL, JR., MD, Clifford W.
Title: SYSTEMS AND METHODS TO REPAIR TISSUE DEFECTS
Abstract:
Methods of bioprinting a bio-ink construct on an internal tissue defect or a chondral defect during a minimally invasive surgery on an individual in need thereof are provided, comprising: visualizing the defect; positioning a bioprinter comprising a printhead within proximity of or in contact with the defect; and ejecting a bio-ink from the printhead onto the defect to form a bio-ink layer, thereby generating a bio-ink construct. Further provided are systems for bioprinting a bio-ink construct on an internal tissue defect during a minimally invasive surgery on an individual in need thereof, comprising a control system, an endoscope, and a bioprinter comprising a printhead.