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1. (WO2017205383) METHOD OF TREATING CYSTIC FIBROSIS AIRWAY DISEASE
Latest bibliographic data on file with the International Bureau    Submit observation

Pub. No.: WO/2017/205383 International Application No.: PCT/US2017/034018
Publication Date: 30.11.2017 International Filing Date: 23.05.2017
IPC:
A61K 9/12 (2006.01) ,A61K 31/70 (2006.01) ,A61K 38/02 (2006.01) ,C07D 473/02 (2006.01) ,C07D 473/16 (2006.01) ,C07D 473/18 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9
Medicinal preparations characterised by special physical form
10
Dispersions; Emulsions
12
Aerosols; Foams
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
70
Carbohydrates; Sugars; Derivatives thereof
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38
Medicinal preparations containing peptides
02
Peptides of undefined number of amino acids; Derivatives thereof
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
D
HETEROCYCLIC COMPOUNDS
473
Heterocyclic compounds containing purine ring systems
02
with oxygen, sulfur, or nitrogen atoms directly attached in positions 2 and 6
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
D
HETEROCYCLIC COMPOUNDS
473
Heterocyclic compounds containing purine ring systems
02
with oxygen, sulfur, or nitrogen atoms directly attached in positions 2 and 6
16
two nitrogen atoms
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
D
HETEROCYCLIC COMPOUNDS
473
Heterocyclic compounds containing purine ring systems
02
with oxygen, sulfur, or nitrogen atoms directly attached in positions 2 and 6
18
one oxygen and one nitrogen atom, e.g. guanine
Applicants: UNIVERSITY OF IOWA RESEARCH FOUNDATION[US/US]; 112 N. Capitol Street 6 Gilmore Hall Iowa City, Iowa 52242-5500, US
Inventors: ZABNER, Joseph; US
WELSH, Michael, J.; US
STOLTZ, David, A.; US
ABOU ALAIWA, Mahmoud; US
Agent: VIKSNINS, Ann, S.; US
HARRIS, Robert, J.; US
MALEN, Peter, L.; US
KRUEGER, Katherine, A.D.; US
MICKELSON, John, W.; US
LI, Yang; US
Priority Data:
62/340,06623.05.2016US
Title (EN) METHOD OF TREATING CYSTIC FIBROSIS AIRWAY DISEASE
(FR) PROCÉDÉ DE TRAITEMENT DE LA FIBROSE KYSTIQUE DES VOIES RESPIRATOIRES
Abstract:
(EN) In certain embodiments, the present invention provides a method of increasing liquid pH on airway surface of a tissue in a patient in need thereof comprising administering an effective amount of a therapeutic composition comprising tromethamine to the patient.
(FR) Dans certains modes de réalisation, la présente invention concerne un procédé permettant d'augmenter le pH du liquide sur la surface des voies respiratoires d'un tissu chez un patient en ayant besoin, comprenant l'administration d'une quantité efficace d'une composition thérapeutique comprenant de la trométhamine.
front page image
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)