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1. (WO2017205254) IMMUNE CELLS EXPRESSING ANTIBODY-COUPLED T-CELL RECEPTOR (ACTR) FOR USE IN INHIBITING CANCER CELLS EXPRESSING SURFACE IMMUNOGLOBULIN
Latest bibliographic data on file with the International Bureau    Submit observation

Pub. No.:    WO/2017/205254    International Application No.:    PCT/US2017/033767
Publication Date: 30.11.2017 International Filing Date: 22.05.2017
IPC:
C07K 16/28 (2006.01), C07K 14/735 (2006.01), C07K 16/30 (2006.01), A61K 39/395 (2006.01), A61K 35/17 (2015.01)
Applicants: UNUM THERAPEUTICS [US/US]; 200 Cambridge Park Drive Suite 3100 Cambridge, MA 02140 (US)
Inventors: HUET, Heather; (US).
ETTENBERG, Seth; (US).
FRAY, Michael; (US).
CHEEMA, Tooba; (US)
Agent: CHEN, Yahua; (US)
Priority Data:
62/340,175 23.05.2016 US
Title (EN) IMMUNE CELLS EXPRESSING ANTIBODY-COUPLED T-CELL RECEPTOR (ACTR) FOR USE IN INHIBITING CANCER CELLS EXPRESSING SURFACE IMMUNOGLOBULIN
(FR) CELLULES IMMUNITAIRES EXPRIMANT UN RÉCEPTEUR DE LYMPHOCYTES T COUPLÉ À UN ANTICORPS (ACTR) À UTILISER DANS L'INHIBITION DE CELLULES CANCÉREUSES EXPRIMANT L'IMMUNOGLOBULINE DE SURFACE
Abstract: front page image
(EN)Disclosed herein are methods of using immune cells expressing chimeric receptors for inhibiting growth of pathogenic cells (e.g., cancer cells or pathogenic B cells) that express a surface immunoglobulin.
(FR)L'invention concerne des méthodes d'utilisation de cellules immunitaires exprimant des récepteurs chimériques pour inhiber la croissance de cellules pathogènes (par exemple, des cellules cancéreuses ou des lymphocytes B pathogènes) qui expriment une immunoglobuline de surface.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)