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1. (WO2017205101) METHODS FOR TREATMENT OF REFRACTORY GENERALIZED MYASTHENIA GRAVIS

Pub. No.:    WO/2017/205101    International Application No.:    PCT/US2017/032767
Publication Date: Fri Dec 01 00:59:59 CET 2017 International Filing Date: Tue May 16 01:59:59 CEST 2017
IPC: A61K 39/395
A61P 21/04
C07K 16/28
C07K 16/46
C07K 16/18
Applicants: ALEXION PHARMACEUTICALS, INC.
Inventors: BEDROSIAN, Camille
O'BRIEN, Fanny
WANG, Jing, Jing
Title: METHODS FOR TREATMENT OF REFRACTORY GENERALIZED MYASTHENIA GRAVIS
Abstract:
The disclosure provides methods of treating myasthenia gravis (MG) in a subject in need thereof by administering to the subject a substance that specifically binds complement component 5 (C5). In certain embodiments, the substance that specifically binds C5 is a binding protein, such as an anti-C5 antibody.