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1. (WO2017204414) METHOD AND APPARATUS FOR ANALYZING DEGREE OF CROSS-CONTAMINATION OF SAMPLE

Pub. No.:    WO/2017/204414    International Application No.:    PCT/KR2016/009451
Publication Date: Fri Dec 01 00:59:59 CET 2017 International Filing Date: Fri Aug 26 01:59:59 CEST 2016
IPC: G06F 19/18
G06F 19/22
C12Q 1/68
Applicants: SAMSUNG ELECTRONICS CO., LTD.
삼성전자 주식회사
SAMSUNG LIFE PUBLIC WELFARE FOUNDATION
사회복지법인 삼성생명공익재단
Inventors: PARK, Donghyun
박동현
SON, Daesoon
손대순
PARK, Woongyang
박웅양
Title: METHOD AND APPARATUS FOR ANALYZING DEGREE OF CROSS-CONTAMINATION OF SAMPLE
Abstract:
Provided are a method and an apparatus for analyzing a degree of cross-contamination of a sample with regard to a target sample, comprising the steps of: acquiring first sequence information of a nucleic acid fragment from each of a target sample and an additional sample, and second sequence information of a nucleic acid fragment from a mixed sample of the target sample and the additional sample; calculating allele frequency from each of the first sequence information and the second sequence information acquired; and comparing the calculated allele frequencies with regard to a specific chromosomal locus. By measuring a degree of cross-contamination between samples at a specific chromosomal locus, the method and the apparatus can guarantee reliability to variation detection results.