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1. (WO2017202311) POLYCRYSTALLINE FORM OF 2-AMINOPYRIMIDINE

Pub. No.:    WO/2017/202311    International Application No.:    PCT/CN2017/085566
Publication Date: Fri Dec 01 00:59:59 CET 2017 International Filing Date: Wed May 24 01:59:59 CEST 2017
IPC: C07D 239/48
C07D 239/47
C07D 401/02
C07D 403/12
A61K 31/505
A61K 31/506
A61K 31/5377
Applicants: SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES
中国科学院上海药物研究所
GUANGZHOU INSTITUTES OF BIOMEDICINE AND HEALTH, CHINESE ACADEMY OF SCIENCES
中国科学院广州生物医药与健康研究院
Inventors: MEI, Xuefeng
梅雪锋
DING, Ke
丁克
DING, Jian
丁健
XIE, Hua
谢华
CHAN, Shingpan
陈成斌
Title: POLYCRYSTALLINE FORM OF 2-AMINOPYRIMIDINE
Abstract:
The present invention provides a polycrystalline form of a 2-aminopyrimidine. The invention specifically provides N-((5-((5-chloro-4-((naphth-2-yl)amino))pyrimidin-2-yl)amino)-2-((N-methyl-N-dimethylaminoethyl)amino)-4-methoxybenzyl)acrylamide, a polycrystalline form thereof, and a manufacturing method and application of same.