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1. (WO2017202295) SALINOMYCIN OXIME ETHER DERIVATIVE, PREPARATION METHOD THEREFOR, AND ANTITUMOR USE THEREOF
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Pub. No.:    WO/2017/202295    International Application No.:    PCT/CN2017/085516
Publication Date: 30.11.2017 International Filing Date: 23.05.2017
IPC:
C07D 493/20 (2006.01), A61K 31/351 (2006.01), A61P 35/00 (2006.01)
Applicants: INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF MEDICAL SCIENCES [CN/CN]; ZHANG, Xubin No.A2, Nan Wei Road, Xicheng District Beijing 100050 (CN)
Inventors: WU, Song; (CN).
ZHOU, Qi; (CN).
ZHANG, Wenxuan; (CN).
WU, Jun; (CN).
LI, Bo; (CN).
LIAN, Xu; (CN).
WANG, Liu; (CN).
HAO, Jie; (CN)
Priority Data:
201610347806.7 24.05.2016 CN
Title (EN) SALINOMYCIN OXIME ETHER DERIVATIVE, PREPARATION METHOD THEREFOR, AND ANTITUMOR USE THEREOF
(FR) DÉRIVÉ D'ÉTHER D'OXIME DE SALINOMYCINE, SON PROCÉDÉ DE PRÉPARATION ET SON UTILISATION POUR LA PRÉPARATION DE MÉDICAMENTS ANTITUMORAUX
(ZH) 盐霉素肟醚衍生物、其制备方法和抗肿瘤用途
Abstract: front page image
(EN)The present invention belongs to the field of pharmaceutical chemistry, and relates to a salinomycin oxime ether derivative, a preparation method therefor, and the use thereof in the preparation of antitumor drugs, in particular the use in the treatment of gastric cancer, breast cancer and colon cancer.
(FR)La présente invention relève du domaine de la chimie pharmaceutique et concerne un dérivé d'éther d'oxime de salinomycine, son procédé de préparation et son utilisation pour la préparation de médicaments antitumoraux, en particulier son utilisation pour le traitement du cancer de l'estomac, du cancer du sein et du cancer du côlon.
(ZH)本发明属于药物化学领域,涉及盐霉素肟醚衍生物以及其制备方法和在制备抗肿瘤药物中的用途,尤其是用于治疗胃癌、乳腺癌和结肠癌的用途。
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: Chinese (ZH)
Filing Language: Chinese (ZH)