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1. (WO2017201612) PRESERVATION OF CELL-FREE NUCLEIC ACIDS IN BIOLOGICAL SAMPLES
Latest bibliographic data on file with the International Bureau    Submit observation

Pub. No.: WO/2017/201612 International Application No.: PCT/CA2017/050587
Publication Date: 30.11.2017 International Filing Date: 16.05.2017
IPC:
C12N 15/10 (2006.01) ,C12N 1/04 (2006.01) ,C12Q 1/68 (2006.01)
Applicants: NORGEN BIOTEK CORP.[CA/CA]; 3430 Schmon Parkway Thorold, Ontario L2V 4Y6, CA
Inventors: HAJ-AHMAD, Taha Alexander; CA
HAJ-AHMAD, Yousef; CA
Agent: WONG, Mee Ling; CA
WILSON, Jenna L. R.; CA
LUE, Henry; CA
Priority Data:
62/342,66727.05.2016US
Title (EN) PRESERVATION OF CELL-FREE NUCLEIC ACIDS IN BIOLOGICAL SAMPLES
(FR) CONSERVATION D'ACIDES NUCLÉIQUES SANS CELLULES DANS DES ÉCHANTILLONS BIOLOGIQUES
Abstract: front page image
(EN) Provided is a composition for preserving cell-free nucleic acids and/or cells in a biological sample and methods for use thereof. The composition comprises at least one volume excluding polymer, at least one osmotic agent and at least one enzyme inhibitor. The composition optionally further comprises at least one metabolic inhibitor. Further, provided is a kit comprising the composition, preferably in a blood collection tube, or the components of the composition.
(FR) La présente invention décrit une composition de conservation d'acides nucléiques sans cellules et/ou de cellules dans un échantillon biologique et leurs procédés d'utilisation. La composition comprend au moins un polymère d'exclusion volumique, au moins un agent osmotique et au moins un inhibiteur enzymatique. La composition comprend en outre éventuellement au moins un inhibiteur métabolique. En outre, est prévue une trousse comprenant la composition, préférablement dans un tube de collecte de sang, ou les composants de la composition.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)