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1. (WO2017201281) TARGETING PD-L1 ON TUMOR CELLS
Latest bibliographic data on file with the International Bureau    Submit observation

Pub. No.: WO/2017/201281 International Application No.: PCT/US2017/033320
Publication Date: 23.11.2017 International Filing Date: 18.05.2017
IPC:
C07K 16/28 (2006.01) ,A61K 39/395 (2006.01) ,G01N 33/68 (2006.01)
Applicants: MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH[US/US]; 200 First Street S.W. Rochester, Minnesota 55905, US
Inventors: RUSSELL, Stephen James; US
RUIZ, Autumn J.; US
AMMAYAPPAN, Arun; US
PENG, Kah-Whye; US
BRETON, Camilo Ayala; US
Agent: LUITJENS, Cameron M.; US
FINN III, J. Patrick; US
Priority Data:
62/338,46618.05.2016US
Title (EN) TARGETING PD-L1 ON TUMOR CELLS
(FR) CIBLAGE DE PD-L1 SUR DES CELLULES TUMORALES
Abstract:
(EN) This document relates to materials and methods for treating cancer. For example, this document provides materials and methods for using PD-L1 targeting domains in bispecific chimeric polypeptides, chimeric transmembrane polypeptides, genetically modified viruses, nucleic acid vectors, and/or fusion-inducing cells to treat cancer.
(FR) La présente invention concerne des matériaux et des méthodes pour traiter le cancer. Par exemple, ce document fournit des matériaux et des procédés pour utiliser des domaines de ciblage de PD-L1 dans des polypeptides chimériques bispécifiques, des polypeptides transmembranaires chimériques, des virus génétiquement modifiés, des vecteurs d'acide nucléique et/ou des cellules induisant la fusion pour traiter le cancer.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)