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1. (WO2017201165) METHODS FOR SUBTYPING OF LUNG ADENOCARCINOMA

Pub. No.:    WO/2017/201165    International Application No.:    PCT/US2017/033110
Publication Date: Fri Nov 24 00:59:59 CET 2017 International Filing Date: Thu May 18 01:59:59 CEST 2017
IPC: C12Q 1/68
C07K 16/30
A61K 38/18
Applicants: GENECENTRIC THERAPEUTICS, INC.
THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL
Inventors: FARUKI, Hawazin
LAI-GOLDMAN, Myla
MAYHEW, Greg
SERODY, Jonathan
PEROU, Charles
HAYES, David Neil
Title: METHODS FOR SUBTYPING OF LUNG ADENOCARCINOMA
Abstract:
Methods and compositions are provided for determining a subtype of lung adenocarcinoma (AD) of an individual by detecting the expression level of at least one classifier biomarker selected from a group of gene signatures for lung adenocarcinoma. Also provided herein are methods and compositions for determining the response of an individual with an adenocarcinoma subtype to a therapy such as immunotherapy.