Search International and National Patent Collections
|1. (WO2017201152) ISOXAZOLE DERIVATIVES AS FXR AGONISTS AND METHODS OF USE THEREOF|
|Applicants:||ENANTA PHARMACEUTICALS, INC.
|Inventors:||OR, Yat Sun
|Title:||ISOXAZOLE DERIVATIVES AS FXR AGONISTS AND METHODS OF USE THEREOF|
The present invention provides compounds of Formula I: and pharmaceutically acceptable salts thereof, pharmaceutical compositions comprising these compounds and methods of using these compounds to treat or prevent a disease or disorder mediated as FXR modulators. Specifically, the present invention relates to isoxazole derivatives useful as agonists for FXR, and methods for their preparation and use.