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1. (WO2017201061) SCALABLE PRODUCTION OF GENETICALLY ENGINEERED NANOFIBROUS MACROSCOPIC MATERIALS VIA FILTRATION
Latest bibliographic data on file with the International Bureau    Submit observation

Pub. No.: WO/2017/201061 International Application No.: PCT/US2017/032923
Publication Date: 23.11.2017 International Filing Date: 16.05.2017
IPC:
C07K 1/14 (2006.01) ,C07K 1/34 (2006.01) ,C07K 14/575 (2006.01) ,C07K 14/585 (2006.01) ,C07K 14/81 (2006.01) ,C12N 9/22 (2006.01)
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
1
General processes for the preparation of peptides
14
Extraction; Separation; Purification
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
1
General processes for the preparation of peptides
14
Extraction; Separation; Purification
34
by filtration, ultrafiltration or reverse osmosis
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
14
Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
435
from animals; from humans
575
Hormones
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
14
Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
435
from animals; from humans
575
Hormones
585
Calcitonins
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
14
Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
81
Protease inhibitors
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
N
MICRO-ORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICRO-ORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
9
Enzymes, e.g. ligases (6.); Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating, or purifying enzymes
14
Hydrolases (3.)
16
acting on ester bonds (3.1)
22
Ribonucleases
Applicants:
PRESIDENT AND FELLOWS OF HARVARD COLLEGE [US/US]; 17 Quincy Street Cambridge, MA 02138, US
Inventors:
JOSHI, Neel, Satish; US
DORVAL COURCHESNE, Noémie-Manuelle; CA
DURAJ-THATTE, Anna, M.; US
NGUYEN, Peter, Q.; US
Agent:
ZACHARAKIS, Maria, Laccotripe; US
BLAZESKI, George; US
BELT, Erik, P.; US
BAI, Mei; US
BOWLES, Anita, M.; US
Priority Data:
62/336,93716.05.2016US
62/401,38929.09.2016US
Title (EN) SCALABLE PRODUCTION OF GENETICALLY ENGINEERED NANOFIBROUS MACROSCOPIC MATERIALS VIA FILTRATION
(FR) PRODUCTION ÉVOLUTIVE DE MATÉRIELS MACROSCOPIQUES NANOFIBREUX GÉNÉTIQUEMENT MODIFIÉS PAR LE BIAIS DE LA FILTRATION
Abstract:
(EN) Provided herein are filtration-based purification methods for amyloid fibers, such as curli fibers, directly from microbial culture, and their fabrication into free-standing thin films. Additionally, methods for recycling amyloid fibers thing films by, for example, disassembly and re-assembly, are disclosed herein.
(FR) L'invention concerne des procédés de purification à base de filtration pour des fibres amyloïdes, telles que des fibres de curli, directement à partir d'une culture microbienne, et leur fabrication en films minces autoportants. En outre, l'invention concerne des procédés de recyclage de films minces de fibres amyloïdes, par exemple, par désassemblage et réassemblage.
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)