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1. (WO2017200997) COMPOSITION AND METHOD OF PREPARATION OF PROTEASE MICROPARTICULATE SLOW RELEASE PREPARATION

Pub. No.:    WO/2017/200997    International Application No.:    PCT/US2017/032831
Publication Date: Fri Nov 24 00:59:59 CET 2017 International Filing Date: Wed May 17 01:59:59 CEST 2017
IPC: C12N 9/50
A61K 38/46
A61K 38/48
C12N 9/64
C12N 9/66
Applicants: HYALO TECHNOLOGIES, LLC
Inventors: JAIN, Shalabh
Title: COMPOSITION AND METHOD OF PREPARATION OF PROTEASE MICROPARTICULATE SLOW RELEASE PREPARATION
Abstract:
Compositions containing microparticles loaded with one or protease enzymes and optionally auxiliary therapeutic agents and methods of treating conditions such as keloids therewith are disclosed. The biodegradable polymer and the protease enzyme therein form a controlled release matrix for extended release of the enzyme after administration to a mammal in need thereof.