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1. (WO2017200934) HYDROPHOBIC INTRAOCULAR LENS
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Pub. No.: WO/2017/200934 International Application No.: PCT/US2017/032698
Publication Date: 23.11.2017 International Filing Date: 15.05.2017
IPC:
A61L 27/16 (2006.01) ,C08L 25/18 (2006.01) ,C08L 27/10 (2006.01) ,C08L 29/02 (2006.01) ,A61F 2/16 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
L
METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION, OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES
27
Materials for prostheses or for coating prostheses
14
Macromolecular materials
16
obtained by reactions only involving carbon-to-carbon unsaturated bonds
C CHEMISTRY; METALLURGY
08
ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
L
COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
25
Compositions of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by an aromatic carbocyclic ring; Compositions of derivatives of such polymers
18
Homopolymers or copolymers of aromatic monomers containing elements other than carbon and hydrogen
C CHEMISTRY; METALLURGY
08
ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
L
COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
27
Compositions of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by a halogen; Compositions of derivatives of such polymers
02
not modified by chemical after-treatment
10
containing bromine or iodine atoms
C CHEMISTRY; METALLURGY
08
ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
L
COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
29
Compositions of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by an alcohol, ether, aldehydo, ketonic, acetal, or ketal radical; Compositions of hydrolysed polymers of esters of unsaturated alcohols with saturated carboxylic acids; Compositions of derivatives of such polymers
02
Homopolymers or copolymers of unsaturated alcohols
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
F
FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, E.G. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
2
Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
02
Prostheses implantable into the body
14
Eye parts, e.g. lenses, corneal implants; Artificial eyes
16
Intraocular lenses
Applicants:
BENZ RESEARCH AND DEVELOPMENT CORP. [US/US]; 6447 Parkland Drive P.O. Box 1839 Sarasota, Florida 34230-1839, US
Inventors:
BENZ, Patrick, H.; US
REBOUL, Adam; US
Agent:
BECK, George; US
SHELTON, Daniel; US
AGARWAL, Pavan K.; US
BERKOWITZ, Benjamin; US
BRINCKERHOFF, Courtenay; US
FELDHAUS, John J.; US
KAMINSKI, Michael D.; US
LAW, Glenn; US
MAEBIUS, Stephen; US
QUILLIN, George E.; US
RAWLINS, Andrew E.; US
SCHORR, Kristel; US
SIMKIN, Michele; US
Priority Data:
15/481,79107.04.2017US
62/337,31816.05.2016US
Title (EN) HYDROPHOBIC INTRAOCULAR LENS
(FR) LENTILLE INTRAOCULAIRE HYDROPHOBE
Abstract:
(EN) A hydrophobic intraocular lens (IOL) with excellent non-glistening characteristics, high Abbe number, excellent mechanical properties comprising at least one copolymer comprising: (a) a first monomeric subunit comprising a polymerized (meth)acrylate group and at least one alkoxyalkoxyalkyl side group, (b) a second monomeric subunit different from the first monomeric subunit comprising a polymerized (meth)acrylate group, at least one side group comprising (i) an aryloxy moiety with at least one halogen, and (ii) an aliphatic carbon moiety linking the aryloxy moiety with the polymerized (meth)acrylate group, wherein the aliphatic carbon moiety comprises at least one hydroxyl substituent and.
(FR) La présente invention concerne une lentille intraoculaire (LIO) hydrophobe ayant d'excellentes caractéristiques de non-scintillement, un nombre d'Abbe élevé, d'excellentes propriétés mécaniques comprenant au moins un copolymère comprenant : (a) une première sous-unité monomère comprenant un groupe (méth)acrylate polymérisé et au moins un groupe latéral alcoxyalcoxyalkyle, (b) une deuxième sous-unité monomère différente de la première sous-unité monomère comprenant un groupe polymérisé (méth)acrylate, au moins un groupe latéral comprenant (i) une fraction aryloxy avec au moins un halogène, et (ii) une fraction de carbone aliphatique liant le fragment aryloxy au groupe (méth)acrylate polymérisé, la fraction de carbone aliphatique comprenant au moins un substituant hydroxyle.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)