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1. (WO2017200852) FORMULATION CONTAINING TLR AGONIST AND METHODS OF USE
Latest bibliographic data on file with the International Bureau    Submit observation

Pub. No.:    WO/2017/200852    International Application No.:    PCT/US2017/032287
Publication Date: 23.11.2017 International Filing Date: 11.05.2017
IPC:
C07K 14/705 (2006.01), A61K 33/06 (2006.01), A61K 35/74 (2015.01), A61K 35/76 (2015.01), A61K 39/00 (2006.01), A61K 39/02 (2006.01), A61K 39/12 (2006.01)
Applicants: INFECTIOUS DISEASE RESEARCH INSTITUTE [US/US]; 1616 Eastlake Avenue East, Suite 400 Seattle, WA 98102 (US)
Inventors: FOX, Christopher B.; (US)
Agent: PESIN-FULOP, Jillian; (US).
AIKEN, Charity; (US).
ARJOMAND, Mehran; (US).
BANKO, Max; (US).
AHN, Sejin; (US)
Priority Data:
62/337,322 16.05.2016 US
Title (EN) FORMULATION CONTAINING TLR AGONIST AND METHODS OF USE
(FR) FORMULATION CONTENANT UN AGONISTE DE TLR ET PROCÉDÉS D'UTILISATION
Abstract: front page image
(EN)Stable aqueous formulations of adjuvant comprising a TLR7/8 agonist or a TLR4 agonist with a helper lipid that are adsorbed to alum are provided. Compositions and methods of using the formulations for stimulating an immune response are also provided.
(FR)L'invention concerne des formulations aqueuses stables d'adjuvant comprenant un agoniste de TLR7/8 ou un agoniste de TLR4 avec un lipide auxiliaire qui sont adsorbés sur du sulfate d'aluminium. L'invention concerne également des compositions et des procédés d'utilisation des formulations pour stimuler une réponse immunitaire.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)