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1. (WO2017198853) NEW ACTIVE COMPOUNDS AGAINST PATHOGENIC MICROORGANISMS

Pub. No.:    WO/2017/198853    International Application No.:    PCT/EP2017/062174
Publication Date: Fri Nov 24 00:59:59 CET 2017 International Filing Date: Sat May 20 01:59:59 CEST 2017
IPC: A61K 38/04
A61P 31/00
Applicants: I.C.F. S.R.L.
Inventors: ROMANI, Antonello
PANCIROLI, Barbara
BARONI, Maria Cristina
ALLODI, Tatiana
Title: NEW ACTIVE COMPOUNDS AGAINST PATHOGENIC MICROORGANISMS
Abstract:
A series of linear peptides is described which are useful for the treatment of pathologies caused by pathogenic microorganisms. Said peptides have a significant antibacterial activity, associated with great stability and resistance to the action of bacterial peptidases, and low or non-existent hemo- or cyto-toxicity. In particular, the disposition of the hydrophobic amino acids alternated with charged amino acids gives the peptides high activity.