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1. (WO2017198695) METHOD AND KIT FOR CAPTURING EXTRACELLULAR VESICLES (EVS) ON A SOLID SURFACE
Latest bibliographic data on file with the International Bureau    Submit observation

Pub. No.: WO/2017/198695 International Application No.: PCT/EP2017/061811
Publication Date: 23.11.2017 International Filing Date: 17.05.2017
IPC:
G01N 33/50 (2006.01) ,G01N 33/543 (2006.01)
Applicants: UNICYTE EV AG[CH/CH]; Aawasserstrasse 2 CH-6370 OBERDORF, CH
Inventors: DEREGIBUS, Maria Chiara; IT
BUSSOLATI, Benedetta; IT
CAMUSSI, Giovanni; IT
DIMUCCIO, Veronica; IT
Agent: COMOGLIO, Elena; IT
JACOBACCI, Guido; IT
QUINTERNO, Giuseppe; IT
RAMBELLI, Paolo; IT
GERBINO, Angelo; IT
FIORAVANTI, Corrado; IT
DEAMBROGI, Edragdo; IT
RONDANO, Davide; IT
VANZINI, Christian; IT
Priority Data:
16170645.220.05.2016EP
Title (EN) METHOD AND KIT FOR CAPTURING EXTRACELLULAR VESICLES (EVS) ON A SOLID SURFACE
(FR) PROCÉDÉ ET KIT POUR CAPTURER DES VÉSICULES EXTRACELLULAIRES (EV) SUR UNE SURFACE SOLIDE
Abstract:
(EN) The invention relates to a method and a kit for capturing on a solid surface the extracellular vesicles (EVs) which are present in a biological fluid sample. The solid surface is coated with a polycationic substance, preferably a protamine salt such as protamine hydrochloride. The method and kit of the invention is useful for the detection and/or quantification of the extracellular vesicles (EVs) which are present in a biological fluid sample, particularly in a diagnostic context.
(FR) La présente invention concerne un procédé et un kit pour capturer sur une surface solide les vésicules extracellulaires (EV) qui sont présentes dans un échantillon de fluide biologique. La surface solide est revêtue d'une substance polycationique, de préférence un sel de protamine tel que le chlorhydrate de protamine. Le procédé et le kit de l'invention sont utiles pour la détection et/ou la quantification des vésicules extracellulaires (EV) qui sont présentes dans un échantillon de fluide biologique, en particulier dans un contexte de diagnostic.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)