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1. (WO2017198258) METHOD FOR FORMING A FUNCTIONAL NETWORK OF HUMAN NEURONAL AND GLIAL CELLS

Pub. No.:    WO/2017/198258    International Application No.:    PCT/DE2017/100408
Publication Date: Fri Nov 24 00:59:59 CET 2017 International Filing Date: Sat May 13 01:59:59 CEST 2017
IPC: A61L 27/22
Applicants: LEIBNIZ-INSTITUT FÜR POLYMERFORSCHUNG DRESDEN E. V.
DEUTSCHES ZENTRUM FÜR NEURODEGENERATIVE ERKRANKUNGEN E. V.
Inventors: PAPADIMITRIOU, Christos
KIZIL, Caghan
FREUDENBERG, Uwe
WERNER, Carsten
Title: METHOD FOR FORMING A FUNCTIONAL NETWORK OF HUMAN NEURONAL AND GLIAL CELLS
Abstract:
The invention relates to a method for forming a functional network of human neuronal and glial cells, wherein the cells are introduced into a synthetic hydrogel system with the components polyethylene glycol (PEG) and heparin and are cultivated therein. The cells are introduced into the PEG heparin hydrogel system together with one of the gel components, either PEG or heparin, with which the cells were previously mixed such that the cells are already located in the hydrogel system during the formation of the three-dimensional hydrogel.