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1. (WO2017197263) METHODS OF TREATING SKIN CANCER BY ADMINISTERING A PD-1 INHIBITOR
Latest bibliographic data on file with the International Bureau    Submit observation

Pub. No.: WO/2017/197263 International Application No.: PCT/US2017/032408
Publication Date: 16.11.2017 International Filing Date: 12.05.2017
IPC:
C07K 16/28 (2006.01) ,A61N 5/00 (2006.01) ,A61N 5/10 (2006.01)
Applicants: REGENERON PHARMACEUTICALS, INC.[US/US]; 777 Old Saw Mill River Road Tarrytown, NY 10591, US
Inventors: LOWY, Israel; US
SIMS, Tasha, N.; US
FURY, Matthew, G.; US
Agent: EL-HIOUM, Dianna G.; US
Priority Data:
62/335,74313.05.2016US
62/340,14223.05.2016US
62/348,54610.06.2016US
62/350,30515.06.2016US
62/364,92021.07.2016US
62/374,02012.08.2016US
62/451,27427.01.2017US
Title (EN) METHODS OF TREATING SKIN CANCER BY ADMINISTERING A PD-1 INHIBITOR
(FR) PROCÉDÉS DE TRAITEMENT DU CANCER DE LA PEAU PAR ADMINISTRATION D'UN INHIBITEUR DE PD-1
Abstract:
(EN) The present disclosure provides methods for treating, reducing the severity, or inhibiting the growth of cancer (e.g., skin cancer). The methods of the present disclosure comprise administering to a subject in need thereof a therapeutically effective amount of a programmed death 1 (PD-1) antagonist (e.g., an anti-PD-1 antibody). In certain embodiments, the skin cancer is cutaneous squamous cell carcinoma or basal cell carcinoma.
(FR) La présente invention concerne des procédés permettant de traiter un cancer (par exemple un cancer de la peau), d'en réduire la gravité ou d'empêcher son développement. Les procédés de la présente invention comprennent l'administration à un sujet dont l'état le nécessite d'une quantité thérapeutiquement efficace d'un antagoniste de la programmed death 1 (PD-1) (par exemple, un anticorps anti-PD-1). Dans certains modes de réalisation, le cancer de la peau est un carcinome cutané à cellules squameuses ou un carcinome basocellulaire.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)