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1. (WO2017197243) CBLB INHIBITION FOR TREATING FUNGAL INFECTIONS
Latest bibliographic data on file with the International Bureau    Submit observation

Pub. No.:    WO/2017/197243    International Application No.:    PCT/US2017/032370
Publication Date: 16.11.2017 International Filing Date: 12.05.2017
IPC:
C12N 15/11 (2006.01), A61K 48/00 (2006.01), A61K 38/00 (2006.01), C07H 21/04 (2006.01)
Applicants: OHIO STATE INNOVATION FOUNDATION [US/US]; 1524 North High Street Columbus, Ohio 43201 (US)
Inventors: ZHANG, Jian; (US).
RAPPLEYE, Chad; (US)
Agent: PRATHER, Donald M.; (US).
HALL, Miles E.; (US).
MEUNIER, Andrew T.; (US).
CARLIN, Gregory J.; (US).
CURFMAN, Christopher L.; (US)
Priority Data:
62/335,901 13.05.2016 US
62/384,526 07.09.2016 US
Title (EN) CBLB INHIBITION FOR TREATING FUNGAL INFECTIONS
(FR) INHIBITION DE CBLB POUR LE TRAITEMENT D'INFECTIONS FONGIQUES
Abstract: front page image
(EN)Disclosed herein is a method for treating a fungal infection in a subject that involves administering to the subject a composition comprising a therapeutically effective amount of a casitas B lymphoma-b (CBLB) inhibitor. Specifically, wherein the CBLB inhibitor is an siRNA. Further disclosed are specific nucleic acid sequences of siRNA CBLB inhibitors.
(FR)L'invention concerne un procédé de traitement d'une infection fongique chez un sujet, qui consiste à administrer au sujet une composition comprenant une quantité thérapeutiquement efficace d'un inhibiteur de lymphome CBL-b (casitas B lymphoma-b). Plus précisément, l'inhibiteur de lymphome CBL-b est un ARNsi. L'invention concerne en outre des séquences d'acides nucléiques spécifiques d'inhibiteurs de CBL-b ARNsi.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)