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1. (WO2017197192) SPIROCYCLE COMPOUNDS AND METHODS OF MAKING AND USING SAME
Latest bibliographic data on file with the International Bureau    Submit observation

Pub. No.:    WO/2017/197192    International Application No.:    PCT/US2017/032276
Publication Date: 16.11.2017 International Filing Date: 11.05.2017
IPC:
C07D 471/10 (2006.01), A61K 31/4747 (2006.01), A61P 25/04 (2006.01)
Applicants: ABIDE THERAPEUTICS, INC. [US/US]; 10835 Road to the Cure, Suite 250 San Diego, California 92121 (US)
Inventors: CISAR, Justin S.; (US).
GRICE, Cheryl A.; (US).
JONES, Todd K.; (US).
WEBER, Olivia D.; (US).
BUZARD, Daniel J.; (US).
SHAGHAFI, Michael B.; (US)
Agent: HOSTETLER, Michael J.; (US)
Priority Data:
62/335,597 12.05.2016 US
Title (EN) SPIROCYCLE COMPOUNDS AND METHODS OF MAKING AND USING SAME
(FR) COMPOSÉS SPIROCYCLIQUES ET PROCÉDÉS DE PRÉPARATION ET D'UTILISATION DE CEUX-CI
Abstract: front page image
(EN)Provided herein are spirocycle compounds and pharmaceutical compositions comprising said compounds. The subject compounds and compositions are useful as modulators of MAGL and/or ABHD6. Furthermore, the subject compounds and compositions are useful for the treatment of pain.
(FR)La présente invention concerne des composés spirocycliques et des compositions pharmaceutiques les contenant. Les composés et les compositions de l'invention sont utiles en tant que modulateurs de MAGL et/ou de ABHD6. Ces composés et ces compositions sont en outre utiles pour le traitement de la douleur.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)