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1. (WO2017197088) LYSYL OXIDASE-LIKE 2 INHIBITORS FOR THE TREATMENT OF INFLAMMATORY CONDITIONS
Latest bibliographic data on file with the International Bureau    Submit observation

Pub. No.:    WO/2017/197088    International Application No.:    PCT/US2017/032115
Publication Date: 16.11.2017 International Filing Date: 11.05.2017
IPC:
A61K 31/44 (2006.01), A61K 31/137 (2006.01), A61K 31/165 (2006.01), C07D 213/16 (2006.01), C07D 401/06 (2006.01), C07D 401/12 (2006.01), C07D 405/06 (2006.01), C07D 405/12 (2006.01)
Applicants: PHARMAKEA, INC. [US/US]; 3030 Bunker Hill Street, Suite 300 San Diego, California 92109 (US)
Inventors: BAIN, Gretchen; (US).
ROWBOTTOM, Martin W.; (US).
HUTCHINSON, John Howard; (US)
Agent: HOSTETLER, Michael J.; (US)
Priority Data:
62/335,263 12.05.2016 US
Title (EN) LYSYL OXIDASE-LIKE 2 INHIBITORS FOR THE TREATMENT OF INFLAMMATORY CONDITIONS
(FR) INHIBITEURS DE LA LYSYL-OXYDASE DE TYPE 2 UTILISÉS POUR LE TRAITEMENT D'ÉTATS PATHOLOGIQUES INFLAMMATOIRES
Abstract: front page image
(EN)Described herein are methods of using LOXL2 inhibitor compounds for the treatment of autoimmune diseases or conditions or inflammatory diseases or conditions in a mammal. Also disclosed are methods for reducing LOXL2 activity in a mammal with an autoimmune disease or condition or an inflammatory disease or condition.
(FR)L'invention concerne des méthodes d'utilisation de composés inhibiteurs de la LOXL2 pour le traitement de maladies ou d'états pathologiques auto-immuns ou de maladies ou d'états pathologiques inflammatoires chez un mammifère. L'invention concerne également des méthodes permettant de réduire l'activité de la LOXL2 chez un mammifère souffrant d'une maladie ou d'un état pathologique auto-immun ou d'une maladie ou d'un état pathologique inflammatoire.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)