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1. (WO2017197080) MODULATORS OF P97 AAA ATPASE ACTIVITY
Latest bibliographic data on file with the International Bureau    Submit observation

Pub. No.: WO/2017/197080 International Application No.: PCT/US2017/032099
Publication Date: 16.11.2017 International Filing Date: 11.05.2017
IPC:
A61K 31/4196 (2006.01) ,A61K 31/44 (2006.01) ,C07D 249/08 (2006.01)
Applicants: UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION[US/US]; 200 Gardner Steel Conference Center Thackeray and O'Hara Streets Pittsburgh, Pennsylvania 15260, US
Inventors: HURYN, Donna, M.; US
WIPF, Peter; US
LAPORTE, Matthew, G.; US
Agent: SIMKIN, Michele; US
AGARWAL, Pavan K.; US
BECK, George; US
BERKOWITZ, Benjamin; US
BRINCKERHOFF, Courtenay; US
FELDHAUS, John J.; US
KAMINSKI, Michael D.; US
LAW, Glenn; US
MAEBIUS, Stephen; US
QUILLIN, George E.; US
RAWLINS, Andrew E.; US
SCHORR, Kristel; US
Priority Data:
62/334,96911.05.2016US
Title (EN) MODULATORS OF P97 AAA ATPASE ACTIVITY
(FR) MODULATEURS DE L'ACTIVITÉ DE L’ATPASE P97 AAA
Abstract:
(EN) The present invention is directed to methods of inhibiting or modulating p97 and compounds and compositions useful in such methods. Diseases and conditions that can be treated with the compounds and compositions of the invention include, but are not limited to, cancer and neurodegenerative disorders susceptible to treatment by modulation or inhibition of p97.
(FR) La présente invention concerne des procédés d'inhibition ou de modulation de la p97, et des composés et des compositions utiles dans de tels procédés. Parmi les maladies et troubles pouvant être traités par les composés et les compositions de l'invention on compte, entre autres, le cancer et les troubles neurodégénératifs sensibles à un traitement par inhibition ou modulation de la p97.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)