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1. (WO2017197027) POLYNUCLEOTIDE ENRICHMENT AND AMPLIFICATION USING ARGONAUTE SYSTEMS
Latest bibliographic data on file with the International Bureau    Submit observation

Pub. No.:    WO/2017/197027    International Application No.:    PCT/US2017/032021
Publication Date: 16.11.2017 International Filing Date: 10.05.2017
IPC:
C12Q 1/68 (2006.01)
Applicants: ILLUMINA, INC. [US/US]; 5200 Illumina Way San Diego, CA 92122 (US)
Inventors: MANDELL, Jeffrey, G.; (US).
HE, Molly; (US)
Agent: MCELHONE, Katharine, E.; (US)
Priority Data:
62/335,012 11.05.2016 US
Title (EN) POLYNUCLEOTIDE ENRICHMENT AND AMPLIFICATION USING ARGONAUTE SYSTEMS
(FR) ENRICHISSEMENT ET AMPLIFICATION DE POLYNUCLÉOTIDES À L'AIDE DE SYSTÈMES D'ARGONAUTE
Abstract: front page image
(EN)A method for enriching or amplifying a target nucleic acid including providing a system having a guide nucleic acid, and a Cas or Argonaute protein or a variant thereof. The guide nucleic acid contains a target-specific nucleotide region substantially complementary to a region of the target nucleic acid, and contacting the target nucleic acid with the system to form a complex.
(FR)L'invention concerne un procédé d'enrichissement et d’amplification d'un acide nucléique cible comprenant la fourniture d'un système à acide nucléique guide, et une protéine Cas ou argonaute ou un variant de celle-ci. L'acide nucléique guide contient une région nucléotidique spécifique d'une cible sensiblement complémentaire d'une région de l'acide nucléique cible; et le procédé consiste à mettre en contact l'acide nucléique cible avec le système pour former un complexe.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)