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1. (WO2017196798) ACCELERATED METHOD FOR PREPARING PLATELET RICH PLASMA
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Pub. No.: WO/2017/196798 International Application No.: PCT/US2017/031680
Publication Date: 16.11.2017 International Filing Date: 09.05.2017
IPC:
B01D 21/00 (2006.01) ,A61M 1/02 (2006.01) ,A61M 1/36 (2006.01)
B PERFORMING OPERATIONS; TRANSPORTING
01
PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
D
SEPARATION
21
Separation of suspended solid particles from liquids by sedimentation
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
M
DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
1
Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
02
Blood transfusion apparatus
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
M
DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
1
Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
36
Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation
Applicants: CHANG, Jae-Hyung, Robert[US/US]; US
INTINI, Guiseppe[US/US]; US
Inventors: CHANG, Jae-Hyung, Robert; US
INTINI, Guiseppe; US
Agent: WATT, Rachel, S.; US
ROMAN, Paul, J.; US
CUTAIA, Alfonzo, I; US
LOPINSKI, John, D.; US
KADLE, Ranjana; US
Priority Data:
62/333,53609.05.2016US
Title (EN) ACCELERATED METHOD FOR PREPARING PLATELET RICH PLASMA
(FR) PROCÉDÉ ACCÉLÉRÉ PERMETTANT DE PRÉPARER UN PLASMA RICHE EN PLAQUETTES
Abstract:
(EN) Provided is an accelerated method for preparing platelet rich plasma (PrP) without centrifugation or filtration. The method comprises contacting a sample of whole blood with an anti-coagulant and an inducer of Rouleaux formation; allowing the mixture to stand thereby depleting the sample of RBCs, and collecting the platelet-rich plasma fraction. The PrP volume obtained by the present method is about 10-60% of the volume of the starting whole blood sample, and contains less than 200,000 RBCs and at least 100,000 platelets per microliter.
(FR) L'invention concerne un procédé accéléré permettant de préparer un plasma riche en plaquettes (PrP) sans centrifugation ni filtration. Le procédé consiste à mettre un échantillon de sang total en contact avec un anticoagulant et un inducteur de formation de Rouleaux ; à permettre au mélange de se tenir debout, réduisant ainsi l'échantillon de RBC, et à recueillir la fraction de plasma riche en plaquettes. Le volume de PrP obtenu par le présent procédé constitue environ 10 à 60 % du volume de l'échantillon de sang total de départ, et comporte moins de 200 000 RBC et au moins 100 000 plaquettes par microlitre.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)