JP2017017932 L-HYDROXYPROLINE-CONTAINING YEAST CELL OR CELL CULTURE PRODUCT OR EXTRACT OF SAME, USE THEREOF, AND METHOD FOR PRODUCING L-HYDROXYPROLINE

1. (WO2017195870) L-HYDROXYPROLINE-CONTAINING YEAST CELL OR CELL CULTURE PRODUCT OR EXTRACT OF SAME, USE THEREOF, AND METHOD FOR PRODUCING L-HYDROXYPROLINE

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Pub. No.:		WO/2017/195870		International Application No.:		PCT/JP2017/017932
Publication Date:		16.11.2017		International Filing Date:		11.05.2017

IPC:

C12N 1/16 (2006.01), A23L 31/10 (2016.01), A23L 31/15 (2016.01), A23L 33/14 (2016.01), A23L 33/175 (2016.01), A61K 8/44 (2006.01), A61K 8/9728 (2017.01), A61K 31/401 (2006.01), A61K 36/06 (2006.01), A61P 17/16 (2006.01), A61P 43/00 (2006.01), A61Q 5/02 (2006.01), A61Q 5/06 (2006.01), A61Q 5/12 (2006.01), A61Q 19/00 (2006.01), A61Q 19/10 (2006.01), C12P 13/24 (2006.01)

Applicants:

SUNTORY HOLDINGS LIMITED [JP/JP]; 1-40, Dojimahama 2-chome, Kita-ku, Osaka-shi, Osaka 5308203 (JP)

Inventors:

NARITA, Yukihiko; (JP).
FUKUI, Yuko; (JP).
MATSUOKA, Tatsuo; (JP)

Agent:

YASUTOMI & ASSOCIATES; 5-36, Miyahara 3-chome, Yodogawa-ku, Osaka-shi, Osaka 5320003 (JP)

Priority Data:

2016-096566

12.05.2016

Title

(EN) L-HYDROXYPROLINE-CONTAINING YEAST CELL OR CELL CULTURE PRODUCT OR EXTRACT OF SAME, USE THEREOF, AND METHOD FOR PRODUCING L-HYDROXYPROLINE
(FR) CELLULE DE LEVURE CONTENANT DE LA L-HYDROXYPROLINE OU PRODUIT DE CULTURE CELLULAIRE OU EXTRAIT DE CELLE-CI, SON UTILISATION ET PROCÉDÉ DE PRODUCTION DE L-HYDROXYPROLINE
(JA) Ｌ－ヒドロキシプロリンを含有する酵母の菌体もしくは菌体培養物又はこれらの抽出物及びその用途並びにＬ－ヒドロキシプロリンの製造方法

Abstract:

(EN)The yeast cell, cell culture product and extract of the same according to the present invention are a cell of at least one kind of yeast selected from the group consisting of Kodamaea ohmeri, Metschnikowia reukaufii, Meyerozyma caribbica, Meyerozyma guilliermondii and Clavispora lusitaniae, a cell culture product thereof and an extract of the same, characterized in that: the yeast cell, cell culture product or extract of the same as described above contains L-hydroxyproline; and the ratio [100 × Hyp/(Pro + Hyp)] of the content (μg/mL) of L-hydroxyproline (Hyp) to the total content (μg/mL) of L-proline (Pro) and L-hydroxyproline is 35-100.
(FR)La cellule de levure, le produit de culture cellulaire et l'extrait de celle-ci selon la présente invention sont une cellule d'au moins un type de levure choisi dans le groupe constitué de Kodamaea ohmerie, Metschnikowia reukaufii, Meyerozyma caribbica, Meyerozyma guilliermondii et Clavispora lusitaniae, un produit de culture cellulaire de celles-ci et un extrait de celles-ci. L'invention est caractérisée en ce que : la cellule de levure, le produit de culture cellulaire ou l'extrait de celle-ci tel que décrits ci-dessus contient de la L-hydroxyproline; et le rapport [100 × Hyp/ (Pro + Hyp)] de la teneur (μg/mL) de L-hydroxyproline (Hyp) sur la teneur totale (μg/mL) de L-proline (Pro) et de L-hydroxyproline est de 35 à 100.
(JA)本発明の酵母の菌体もしくは菌体培養物又はこれらの抽出物は、コダマエア・オウメリ(Kodamaea ohmeri)、メチニコビア・ロイカウフィ（Metschnikowia reukaufii）、メイエロザイマ・カリビカ（Meyerozyma caribbica）、メイエロザイマ・ギリエルモンディ（Meyerozyma guilliermondii）及びクラビスポラ・ルシタニエ（Clavispora lusitaniae）からなる群より選択される少なくとも１種の酵母の菌体もしくは菌体培養物又はこれらの抽出物であって、上記酵母の菌体もしくは菌体培養物又はこれらの抽出物は、Ｌ－ヒドロキシプロリンを含有し、Ｌ－プロリン（Ｐｒｏ）及びＬ－ヒドロキシプロリン（Ｈｙｐ）の合計含量（μｇ／ｍＬ）に対するＬ－ヒドロキシプロリンの含量（μｇ／ｍＬ）の割合（１００×Ｈｙｐ／（Ｐｒｏ＋Ｈｙｐ））が、３５～１００であることを特徴とする。

Designated States:

AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).

Publication Language:	Japanese (JA)
Filing Language:	Japanese (JA)

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