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1. (WO2017195136) SMALL MOLECULE N-(ALPHA-PEROXY) INDOLE COMPOUNDS AND METHODS OF USE
Latest bibliographic data on file with the International Bureau    Submit observation

Pub. No.: WO/2017/195136 International Application No.: PCT/IB2017/052742
Publication Date: 16.11.2017 International Filing Date: 10.05.2017
IPC:
C07D 209/08 (2006.01) ,C07D 209/16 (2006.01) ,C07D 209/24 (2006.01) ,C07D 209/48 (2006.01) ,A61K 31/404 (2006.01) ,A61K 31/4045 (2006.01) ,A61P 33/06 (2006.01)
Applicants: KING ABDULLAH UNIVERSITY OF SCIENCE AND TECHNOLOGY[SA/SA]; Technology Transfer Office 4700 King Abdullah University of Science and Technology Thuwal, 23955-6900, SA
Inventors: WANG, Xinbo; SA
LAI, Zhiping; SA
PAN, Yupeng; SA
HUANG, Kuowei; SA
WANG, Zhigang; CN
Priority Data:
62/334,51811.05.2016US
Title (EN) SMALL MOLECULE N-(ALPHA-PEROXY) INDOLE COMPOUNDS AND METHODS OF USE
(FR) COMPOSÉS DE N-(ALPHA-PEROXY)INDOLE À PETITES MOLÉCULES ET LEURS PROCÉDÉS D'UTILISATION
Abstract: front page image
(EN) The invention relates to novel N-(α-peroxy)indole compounds of Formula I and methods for use. (I) The N-(α-peroxy)indole compounds described herein are useful for treating or preventing parasitic infections, bacterial infections, and cancer in subjects. The methods include administering an N-(α-peroxy)indole compound as described herein to a subject. Also described herein are methods for synthesizing N-(α-peroxy )indole compounds.
(FR) L'invention concerne de nouveaux composés N-(α-peroxy)indole de formule I et leurs procédés d'utilisation. (I) Les composés N-(α-peroxy)indole décrits dans la présente invention sont utiles pour le traitement ou la prévention d'infections parasitaires, d'infections bactériennes et du cancer chez des sujets. Les procédés consistent à administrer un composé N-(α-peroxy)indole tel que décrit dans la présente invention à un sujet. La présente invention concerne également des procédés pour synthétiser des composés N-(α-peroxy)indole.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)