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1. (WO2017194668) DETECTION OF MET EXON 14 DELETIONS AND ASSOCIATED THERAPIES
Latest bibliographic data on file with the International Bureau    Submit observation

Pub. No.:    WO/2017/194668    International Application No.:    PCT/EP2017/061310
Publication Date: 16.11.2017 International Filing Date: 11.05.2017
IPC:
C12Q 1/68 (2006.01)
Applicants: ROCHE DIAGNOSTICS GMBH [DE/DE]; Sandhofer Straße 116 68305 Mannheim (DE) (DE only).
F. HOFFMANN-LA ROCHE AG [CH/CH]; Grenzacherstrasse 124 4070 Basel (CH) (AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BE, BF, BG, BH, BJ, BN, BR, BW, BY, BZ, CA, CF, CG, CH, CI, CL, CM, CN, CO, CR, CU, CY, CZ, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, FR, GA, GB, GD, GE, GH, GM, GN, GQ, GR, GT, GW, HN, HR, HU, ID, IE, IL, IN, IR, IS, IT, JP, KE, KG, KH, KM, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LT, LU, LV, LY, MA, MC, MD, ME, MG, MK, ML, MN, MR, MT, MW, MX, MY, MZ, NA, NE, NG, NI, NL, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SI, SK, SL, SM, SN, ST, SV, SY, SZ, TD, TG, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, UZ, VC, VN, ZA, ZM, ZW only).
ROCHE MOLECULAR SYSTEMS, INC. [US/US]; 4300 Hacienda Drive Pleasanton, California 94588 (US) (US only)
Inventors: CHEUNG, Cindy; (US).
HILLMAN, Grantland; (US).
MA, Xiaoju Max; (US).
MANOHAR, Chitra; (US).
WONG, Lily; (US)
Agent: SCHWARZ, Ralf; (DE).
IMMENDOERFER-RUEHLE, Ulrike; (DE).
KNAUER, Martin; (DE).
LOHE, Hans-Joerg; (DE).
MUSSAUER, Heiko; (DE).
RAUSCHER, Andreas; (DE).
VON CAMPENHAUSEN, Harald; (DE).
HOEVELMANN, Sascha; (DE).
RIWOTZKI, Karsten; (DE).
KUNSTMANN, Tobias; (DE).
RITTER, Claudia; (DE).
MEINEL, Anne Julia; (DE).
MOLNAR, Ferenc; (DE)
Priority Data:
62/336,362 13.05.2016 US
Title (EN) DETECTION OF MET EXON 14 DELETIONS AND ASSOCIATED THERAPIES
(FR) DÉTECTION DE DÉLÉTIONS DE L'EXON 14 DU GÈNE MET ET TRAITEMENTS ASSOCIÉS
Abstract: front page image
(EN)Provided herein are methods and compositions to detect MET exon 14 skipping using RT-PCR, and methods of treating individuals with MET exon 14 deleted cancers.
(FR)L'invention concerne des procédés et des compositions pour détecter le saut de l'exon 14 du gène MET par RT-PCR, et des méthodes de traitement de sujets atteints de cancers où l'exon 14 du gène MET a été supprimé.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)