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1. (WO2017194605) METHODS FOR MODULATING PROTEIN GALACTOSYLATION PROFILES OF RECOMBINANT PROTEINS USING PERACETYL GALACTOSE
Latest bibliographic data on file with the International Bureau    Submit observation

Pub. No.: WO/2017/194605 International Application No.: PCT/EP2017/061181
Publication Date: 16.11.2017 International Filing Date: 10.05.2017
IPC:
C12P 21/00 (2006.01)
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
P
FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
21
Preparation of peptides or proteins
Applicants: ARES TRADING S.A.[CH/CH]; Zone Industrielle de L'Ouriettaz 1170 Aubonne, CH
Inventors: JORDAN, Martin; CH
LECLERCQ, Gabrielle; CH
SOUQUET, Jonathan; CH
BROLY, Hervé; CH
BRUHLMANN, David; CH
Agent: MERCK SERONO S.A.; Intellectual Property Terre Bonne Business Park A2 Route de Crassier 15 1162 Eysins, CH
Priority Data:
16169062.310.05.2016EP
Title (EN) METHODS FOR MODULATING PROTEIN GALACTOSYLATION PROFILES OF RECOMBINANT PROTEINS USING PERACETYL GALACTOSE
(FR) PROCÉDÉS DE MODULATION DE PROFILS DE GALACTOSYLATION DE PROTÉINES DE PROTÉINES RECOMBINANTES À L'AIDE DE GALACTOSE PERACÉTYLE
Abstract:
(EN) The present invention relates to methods and compositions for modulating glycosylation profile, such as the galactosylation profile, of recombinant proteins expressed by mammalian host cells during the cell culture process by supplementing cell culture media with a peracetyl galactose.
(FR) La présente invention concerne des procédés et des compositions permettant de moduler le profil de glycosylation, notamment le profil de galactosylation de protéines recombinantes exprimées par des cellules hôtes de mammifères pendant le processus de culture cellulaire en complétant des milieux de culture cellulaire avec un galactose peracétyle.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)