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1. (WO2017194499) TISSUE-SPECIFIC EXOSOMES AS BIOMARKERS

Pub. No.:    WO/2017/194499    International Application No.:    PCT/EP2017/060989
Publication Date: Fri Nov 17 00:59:59 CET 2017 International Filing Date: Wed May 10 01:59:59 CEST 2017
IPC: C12Q 1/68
G01N 33/50
C07K 16/18
C07K 16/28
C07K 16/40
Applicants: HELMHOLTZ ZENTRUM MÜNCHEN - DEUTSCHES FORSCHUNGSZENTRUM FÜR GESUNDHEIT UND UMWELT (GMBH)
Inventors: STEMMER, Kerstin
TSCHÖP, Matthias
BAUER, Michaela
ZEIDLER, Reinhard
FEEDERLE, Regina
Title: TISSUE-SPECIFIC EXOSOMES AS BIOMARKERS
Abstract:
In general, the present invention relates to the field of (bio-)medicine and in particular to various metabolic diseases. Specifically, the invention provides means and methods for diagnosing, monitoring and predicting the risk for developing metabolic diseases. The invention uses exosomes as biomarkers for the aforementioned purposes. Moreover, an antibody of the present invention capable of specifically recognizing tissue-specific exosomes is also provided.