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1. (WO2017194424) MUTANT YEAST STRAINS WITH ENHANCED PRODUCTION OF ERYTHRITOL OR ERYTHRULOSE

Pub. No.:    WO/2017/194424    International Application No.:    PCT/EP2017/060823
Publication Date: Fri Nov 17 00:59:59 CET 2017 International Filing Date: Sat May 06 01:59:59 CEST 2017
IPC: C12P 7/18
C12N 1/16
C12N 9/12
C12N 9/04
Applicants: INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE
UNIVERSITE LIBRE DE BRUXELLES
UNIVERSITE DE LIEGE
Inventors: NICAUD, Jean-Marc
FICKERS, Patrick
CARLY, Frederic
Title: MUTANT YEAST STRAINS WITH ENHANCED PRODUCTION OF ERYTHRITOL OR ERYTHRULOSE
Abstract:
The invention relates to a method for enhancing the erythritol and/or erythrulose productivity and/or yield of an erythritol and/or erythrulose-producing yeast strain, such as Yarrowia lipolytica, comprising inhibiting in said yeast strain the expression or the activity of an endogenous L-erythrulose kinase and/or erythritol dehydrogenase. The invention also relates to a mutant yeast strain obtained by said method.