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1. (WO2017193535) ALUMINUM HYDROXIDE GEL-SODIUM CHLORIDE COMPOSITE IMMUNOLOGIC ADJUVANT, AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF
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Pub. No.: WO/2017/193535 International Application No.: PCT/CN2016/102131
Publication Date: 16.11.2017 International Filing Date: 14.10.2016
Chapter 2 Demand Filed: 13.03.2018
IPC:
A61K 39/39 (2006.01) ,A61K 39/02 (2006.01) ,A61K 39/29 (2006.01) ,A61K 39/12 (2006.01) ,A61P 35/00 (2006.01) ,A61P 1/16 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39
Medicinal preparations containing antigens or antibodies
39
characterised by the immunostimulating additives, e.g. chemical adjuvants
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39
Medicinal preparations containing antigens or antibodies
02
Bacterial antigens
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39
Medicinal preparations containing antigens or antibodies
12
Viral antigens
29
Hepatitis virus
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39
Medicinal preparations containing antigens or antibodies
12
Viral antigens
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
35
Antineoplastic agents
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
1
Drugs for disorders of the alimentary tract or the digestive system
16
for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
Applicants: SI CHUAN UNIVERSITY[CN/CN]; No.24, South Section 1, First Ring Road, Wuhou District Chengdu, Sichuan 610065, CN
Inventors: WEI, Xiawei; CN
LUO, Min; CN
WEI, Yuquan; CN
Agent: CHENGDU HONGQIAO PATENT LAW OFFICE; Room 301-305, 306-1, 318-320, 3rd Floor Building 1, No.259 Tianren Road, Hi-Tech Zone Chengdu, Sichuan 610000, CN
Priority Data:
201610318724.X13.05.2016CN
Title (EN) ALUMINUM HYDROXIDE GEL-SODIUM CHLORIDE COMPOSITE IMMUNOLOGIC ADJUVANT, AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF
(FR) ADJUVANT IMMUNOLOGIQUE COMPOSITE GEL D'HYDROXYDE D'ALUMINIUM-CHLORURE DE SODIUM, SON PROCÉDÉ DE PRÉPARATION ET SES APPLICATIONS
(ZH) 氢氧化铝凝胶-氯化钠复合免疫佐剂及其制备方法和用途
Abstract:
(EN) An aluminum hydroxide gel-sodium chloride composite immunologic adjuvant, and a preparation method therefor and application thereof. A technical problem to be resolved is to provide an immunologic adjuvant with good performance. A technical solution to resolve the technical problem is to provide application of sodium chloride in immunologic adjuvant preparation and an aluminum hydroxide gel-sodium chloride composite immunologic adjuvant obtained based on the sodium chloride. The composite immunologic adjuvant mainly contains aluminum hydroxide gel and sodium chloride, has the advantages of being simple in method, low in costs, high in immunological competence, high in clinical safety, and the like, is an excellent composite immunologic adjuvant for various antigens, and provides an effective option for vaccine development and application.
(FR) Adjuvant immunologique composite gel d'hydroxyde d'aluminium-chlorure de sodium, son procédé de préparation et ses applications. Le problème technique à résoudre consiste à obtenir un adjuvant immunologique ayant de bonnes performances. Une solution technique pour résoudre le problème technique consiste à appliquer du chlorure de sodium dans une préparation adjuvante immunologique et un adjuvant immunologique composite gel d'hydroxyde d'aluminium-chlorure de sodium obtenu à partir du chlorure de sodium. L'adjuvant immunologique composite contient principalement du gel d'hydroxyde d'aluminium et du chlorure de sodium, présente pour avantages d'être simple à mettre en œuvre, de faible coût, de compétence immunologique élevée, de sécurité clinique élevée, etc. est un excellent adjuvant immunologique composite pour divers antigènes, et fournit une option efficace pour le développement et l'application de vaccins.
(ZH) 一种氢氧化铝凝胶-氯化钠复合免疫佐剂及其制备方法和用途。所要解决的技术问题是提供一种性能良好的免疫佐剂。解决该技术问题的技术方案是提供氯化钠在制备免疫佐剂中用途以及以之为基础得到的氢氧化铝凝胶-氯化钠复合免疫佐剂。该复合免疫佐剂主要含有氢氧化铝凝胶和氯化钠,具有方法简便、成本低、免疫活性强、临床安全性高等优点,是一种优秀的可用于各种抗原的复合免疫佐剂,为疫苗的开发和应用提供了有效选择。
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: Chinese (ZH)
Filing Language: Chinese (ZH)