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1. (WO2017193115) SYNAPTIC PROTEIN BIOMARKERS AND DIFFERENTIAL DIAGNOSIS OF ALZHEIMER'S DISEASE AND OTHER NEURODEGENERATIVE DISORDERS
Latest bibliographic data on file with the International Bureau    Submit observation

Pub. No.:    WO/2017/193115    International Application No.:    PCT/US2017/031487
Publication Date: 09.11.2017 International Filing Date: 07.05.2017
IPC:
G01N 33/53 (2006.01), G01N 33/68 (2006.01)
Applicants: NANOSOMIX, INC. [US/US]; 27068 La Paz Road, Suite 555 Aliso Viejo, CA 92656 (US)
Inventors: GOETZL, Edward J.; (US)
Agent: JACOB, Christopher T.; (US)
Priority Data:
62/332,479 06.05.2016 US
Title (EN) SYNAPTIC PROTEIN BIOMARKERS AND DIFFERENTIAL DIAGNOSIS OF ALZHEIMER'S DISEASE AND OTHER NEURODEGENERATIVE DISORDERS
(FR) BIOMARQUEURS DE PROTÉINES SYNAPTIQUES ET DIAGNOSTIC DIFFÉRENTIEL DE LA MALADIE D'ALZHEIMER ET D'AUTRES TROUBLES NEURODÉGÉNÉRATIFS
Abstract: front page image
(EN)The present invention relates to synaptic protein biomarkers and diagnostic and prognostic methods for Alzheimer's disease and other neurodegenerative disorders. The invention also provides compositions for detecting the synaptic protein biomarkers as well as compositions and methods useful for early diagnosis and/or treatment of Alzheimer's disease and other neurodegenerative disorders. The invention also provides methods for detecting biomarkers in vesicles (e.g., exosomes) isolated from a biological sample.
(FR)La présente invention concerne des biomarqueurs et des méthodes de diagnostic et de pronostic de la maladie d'Alzheimer et d'autres troubles neurodégénératifs. L'invention concerne également des compositions permettant de détecter les biomarqueurs de protéines synaptiques ainsi que des compositions et des méthodes utiles pour le diagnostic et/ou le traitement précoces de la maladie d'Alzheimer et d'autres troubles neurodégénératifs. L'invention concerne en outre des méthodes de détection de biomarqueurs dans des vésicules (par ex., des exosomes) isolées à partir d'un échantillon biologique.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)