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1. (WO2017193101) DNA ANTIBODY CONSTRUCTS FOR USE AGAINST PSEUDOMONAS AERUGINOSA
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Pub. No.: WO/2017/193101 International Application No.: PCT/US2017/031449
Publication Date: 09.11.2017 International Filing Date: 05.05.2017
IPC:
A61K 39/40 (2006.01) ,C07K 16/00 (2006.01) ,C07K 16/12 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39
Medicinal preparations containing antigens or antibodies
395
Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
40
bacterial
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
16
Immunoglobulins, e.g. monoclonal or polyclonal antibodies
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
16
Immunoglobulins, e.g. monoclonal or polyclonal antibodies
12
against material from bacteria
Applicants:
THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA [US/US]; 3160 Chestnut Street, Suite 200 Philadelphia, PA 19104, US
THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY [US/US]; 3601 Spruce Street Philadelphia, PA 19104, US
INOVIO PHARMACEUTICALS, INC. [US/US]; 660 Germantown Pike, Suite 110 Plymouth Meeting, PA 19462, US
Inventors:
WEINER, David; US
PATEL, Ami; US
YAN, Jian; US
Agent:
NGUYEN, Quang, D.; US
Priority Data:
62/332,36305.05.2016US
Title (EN) DNA ANTIBODY CONSTRUCTS FOR USE AGAINST PSEUDOMONAS AERUGINOSA
(FR) CONSTRUCTIONS D'ANTICORPS ANTI-ADN POUR UTILISATION CONTRE PSEUDOMONAS AERUGINOSA
Abstract:
(EN) Disclosed herein are mono and bispecific DNA antibodies (DMAbs) targeting Pseudomonas aeruginosa. Also disclosed herein is a method of generating a synthetic antibody in a subject by administering the DMAbs to the subject. The disclosure also provides a method of preventing and/or treating Pseudomonas aeruginosa infection in a subject using said composition and method of generation.
(FR) L'invention concerne des anticorps anti-ADN mono- et bispécifiques ciblant Pseudomonas aeruginosa. L'invention concerne également un procédé de génération d'un anticorps synthétique chez un sujet par l'administration de ces anticorps anti-ADN au sujet. L'invention concerne aussi une méthode de prévention et/ou de traitement de l'infection par Pseudomonas aeruginosa chez un sujet en utilisant ladite composition et ledit procédé de génération.
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)