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1. (WO2017193097) METHODS AND COMPOSITIONS FOR DETERMINING SPECIFC TCR AND BCR CHAIN PAIRINGS
Latest bibliographic data on file with the International Bureau    Submit observation

Pub. No.:    WO/2017/193097    International Application No.:    PCT/US2017/031444
Publication Date: 09.11.2017 International Filing Date: 05.05.2017
IPC:
C12Q 1/68 (2006.01), G01N 33/50 (2006.01), G01N 33/58 (2006.01), G01N 33/53 (2006.01)
Applicants: GIRIHLET INC. [US/US]; 161 N 4th Street, Apt 4C Brooklyn, NY 11211 (US)
Inventors: JAYAPRAKASH, Anitha; (US)
Agent: LORENZ, Todd, A.; (US)
Priority Data:
62/333,110 06.05.2016 US
Title (EN) METHODS AND COMPOSITIONS FOR DETERMINING SPECIFC TCR AND BCR CHAIN PAIRINGS
(FR) PROCÉDÉS ET COMPOSITIONS PERMETTANT DE DÉTERMINER DES APPARIEMENTS DE CHAÎNES TCR ET BCR SPÉCIFIQUES
Abstract: front page image
(EN)Provided are methods for determining TCR α/γ and TCR β/δ chain pairings in T cell(s) of interest within a population of T cells, comprising a combination of selecting for the T cell(s) of interest based on the TCR α/δ or TCR β/δ chain followed by sequencing of the counterpart TCR β/δ or TCR α/γ chain, respectively.
(FR)L'invention concerne des procédés permettant de déterminer des appariements de chaînes TCR α/γ et TCR β/δ dans une ou des cellules T d'intérêt au sein d'une population de cellules T, comprenant la combinaison du choix de la ou des cellules T d'intérêt sur la base de leur chaîne TCR α/δ ou TCR β/δ, suivi par le séquençage de la chaîne TCR β/δ ou TCR α/γ de contrepartie, respectivement.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)