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1. (WO2017193084) TLR9-TARGETED SPHERICAL NUCLEIC ACIDS HAVING POTENT ANTITUMOR ACTIVITY
Latest bibliographic data on file with the International Bureau    Submit observation

Pub. No.:    WO/2017/193084    International Application No.:    PCT/US2017/031423
Publication Date: 09.11.2017 International Filing Date: 05.05.2017
IPC:
C12N 15/117 (2010.01), A61K 31/7088 (2006.01), A61K 31/7125 (2006.01), A61K 9/127 (2006.01), A61K 47/50 (2017.01), A61K 39/395 (2006.01), A61P 35/00 (2006.01)
Applicants: EXICURE, INC. [US/US]; 8045 Lamon Avenue Suite 410 Skokie, IL 60077-5318 (US)
Inventors: NALLAGATLA, Subbarao; (US).
ANDERSON, Bart; (US).
KANDIMALLA, Ekambar; (US)
Agent: LOCKHART, Helen, C.; (US)
Priority Data:
62/333,139 06.05.2016 US
62/480,936 03.04.2017 US
Title (EN) TLR9-TARGETED SPHERICAL NUCLEIC ACIDS HAVING POTENT ANTITUMOR ACTIVITY
(FR) ACIDES NUCLÉIQUES SPHÉRIQUES CIBLANT TLR9, AYANT UNE ACTIVITÉ ANTITUMORALE PUISSANTE
Abstract: front page image
(EN)Aspects of the invention relate to immunostimulatory spherical nucleic acids (IS- SNA) for the treatment of a disorder, such as cancer. The IS-SNA may be administered together with a checkpoint inhibitor.
(FR)Des aspects de l'invention concernent des acides nucléiques sphériques immunostimulateurs (IS-SNA) pour le traitement d'un trouble, tel que le cancer. Les IS-SNA peut être administrés conjointement avec un inhibiteur de point de contrôle.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)