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1. (WO2017193021) SEPARATION OF RARE CELLS AND GENOMIC ANALYSIS THEREOF
Latest bibliographic data on file with the International Bureau    Submit observation

Pub. No.:    WO/2017/193021    International Application No.:    PCT/US2017/031341
Publication Date: 09.11.2017 International Filing Date: 05.05.2017
IPC:
G01N 21/64 (2006.01), G01N 21/62 (2006.01)
Applicants: EMORY UNIVERSITY [US/US]; Office of Technology Transfer 1599 Clifton Road NE, 4th Floor Atlanta, Georgia 30322 (US)
Inventors: MARCUS, Adam; (US).
KONEN, Jessica; (US)
Agent: MASON, James C.; (US).
FRITTS, Laura; (US).
ISAACS, Randi; (US).
SHERER, Todd; (US)
Priority Data:
62/332,631 06.05.2016 US
Title (EN) SEPARATION OF RARE CELLS AND GENOMIC ANALYSIS THEREOF
(FR) SÉPARATION DE CELLULES RARES ET ANALYSE GÉNOMIQUE DE CES DERNIÈRES
Abstract: front page image
(EN)This disclosure relates to method of isolating rare cells, e.g. unique cancer cells. In certain embodiments, the disclosure contemplates methods of identifying unique cells that are in a sample that contains a group of cells that are replicating at unique locations and/or at different rates. In certain embodiments the uniquely isolated and/or identified cells are evaluated for genetic content and/or expression for diagnostic evaluations. In certain embodiments, the disclosure contemplates compositions comprising cells that are derived from methods disclosed herein.
(FR)L'invention concerne un procédé d'isolement de cellules rares, par exemple des cellules cancéreuses uniques. Dans certains modes de réalisation, l'invention concerne des procédés d'identification de cellules uniques qui se trouvent dans un échantillon qui contient un groupe de cellules qui se répliquent à des emplacements uniques et/ou à des vitesses différentes. Dans certains modes de réalisation, les cellules isolées et/ou identifiées de manière unique sont évaluées pour leur contenu et/ou expression génétique pour des évaluations diagnostiques. Dans certains modes de réalisation, l'invention concerne des compositions comprenant des cellules qui sont dérivées des procédés de l'invention.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)