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1. (WO2017192991) SELECTIVE ESTROGEN RECEPTOR DOWN-REGULATORS (SERDS)
Latest bibliographic data on file with the International Bureau    Submit observation

Pub. No.: WO/2017/192991 International Application No.: PCT/US2017/031297
Publication Date: 09.11.2017 International Filing Date: 05.05.2017
IPC:
C07F 5/04 (2006.01) ,A61K 31/69 (2006.01)
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
F
ACYCLIC, CARBOCYCLIC, OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
5
Compounds containing elements of the 3rd Group of the Periodic System
02
Boron compounds
04
Esters of boric acids
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
69
Boron compounds
Applicants: XAVIER UNIVERSITY OF LOUISIANA[US/US]; Office of Resource Development 1 Drexel Drive, Box 68 New Orleans, LA 70125, US
Inventors: WANG, Guangdi; US
LIU, Jiawang; US
ZHENG, Shilong; US
ZHONG, Qiu; US
GUO, Shanchun; US
Agent: MOORE, Chester, G.; US
Priority Data:
62/332,54106.05.2016US
Title (EN) SELECTIVE ESTROGEN RECEPTOR DOWN-REGULATORS (SERDS)
(FR) RÉGULATEURS NÉGATIFS SÉLECTIFS DU RÉCEPTEUR DES OESTROGÈNES (SERD)
Abstract:
(EN) The present disclosure relates to orally bioavailable selective estrogen receptor down-regulators (SERDs) and the synthesis of the same. Further, the present disclosure teaches the utilization of the orally bioavailable selective estrogen receptor down-regulators (SERDs) in a treatment for proliferative diseases, including cancer, particularly breast cancer, and especially ER+ breast cancer.
(FR) La présente invention concerne des régulateurs négatifs sélectifs du récepteur des oestrogènes (SERD) biodisponibles par voie orale, et la synthèse de ceux-ci. En outre, la présente invention concerne l'utilisation des régulateurs négatifs sélectifs du récepteur des oestrogènes (SERD) biodisponibles par voie orale dans un traitement de maladies prolifératives, y compris le cancer, en particulier le cancer du sein, et en particulier le cancer du sein ER+.
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)