WIPO logo
Mobile | Deutsch | Español | Français | 日本語 | 한국어 | Português | Русский | 中文 | العربية |
PATENTSCOPE

Search International and National Patent Collections
World Intellectual Property Organization
Search
 
Browse
 
Translate
 
Options
 
News
 
Login
 
Help
 
Machine translation
1. (WO2017192850) FLUOROPHORE-BASED KINASE SENSORS
Latest bibliographic data on file with the International Bureau    Submit observation

Pub. No.:    WO/2017/192850    International Application No.:    PCT/US2017/031059
Publication Date: 09.11.2017 International Filing Date: 04.05.2017
IPC:
C12Q 1/48 (2006.01), C07K 7/06 (2006.01), C07D 215/36 (2006.01)
Applicants: ASSAYQUANT TECHNOLOGIES, INC. [US/US]; 260 Cedar Hill Street Marlborough, MA 01752 (US)
Inventors: SCHAEFER, Erik, M.; (US).
IMPERIALI, Barbara; (US)
Agent: GORDON, Dana, M.; (US).
BENNETT, Jonathan, D.; (US).
ABELLEIRA, Susan, A.; (US).
AKHIEZER, Alexander; (US).
BLOUNT, Jennifer, V.; (US)
Priority Data:
62/331,903 04.05.2016 US
Title (EN) FLUOROPHORE-BASED KINASE SENSORS
(FR) CAPTEURS DE KINASE À BASE DE FLUOROPHORES
Abstract: front page image
(EN)Disclosed are metal-binding analytical reagents that exhibit chelation-enhanced fluorescence (CHEF) upon binding to Mg2+. Also disclosed are methods of using the reagents for detecting the presence of or quantifying the activity of individual kinases or groups of kinases in a sample.
(FR)L'invention concerne des réactifs analytiques se liant aux métaux, qui présentent une fluorescence améliorée par chélation (CHEF) lors de la liaison à Mg2+. L'invention concerne également des méthodes d'utilisation des réactifs pour détecter la présence de l'activité de kinases individuelles ou de groupes de kinases dans un échantillon ou la quantifier.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)