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1. (WO2017192760) THERAPEUTIC CELL WASHING, CONCENTRATION, AND SEPARATION UTILIZING ACOUSTOPHORESIS

Pub. No.:    WO/2017/192760    International Application No.:    PCT/US2017/030903
Publication Date: Fri Nov 10 00:59:59 CET 2017 International Filing Date: Thu May 04 01:59:59 CEST 2017
IPC: A61J 3/00
A61K 35/12
A61K 35/14
C12N 13/00
C12M 1/00
Applicants: FLODESIGN SONICS, INC.
Inventors: LIPKENS, Bart
PRESZ, Walter M. Jr
DUTRA, Brian
GILMANSHIN, Rudolf
DIONNE, Jason
LEIDEL, Chris
MASI, Louis
GHOSHAL, Goutam
Title: THERAPEUTIC CELL WASHING, CONCENTRATION, AND SEPARATION UTILIZING ACOUSTOPHORESIS
Abstract:
Multi-stage acoustophoretic devices for continuously separating a second fluid or a particulate from a host fluid are disclosed. Methods of operating the multi-stage acoustophoretic devices are also disclosed. The systems include multiple acoustophoretic devices fluidly connected to one another in series, each acoustophoretic device comprising a flow chamber, an ultrasonic transducer capable of creating a multi-dimensional acoustic standing wave, and a reflector. The systems can further include pumps and flowmeters.