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1. (WO2017192739) SYSTEM AND METHOD FOR DISTINGUISHING BLOOD COMPONENTS
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Pub. No.: WO/2017/192739 International Application No.: PCT/US2017/030870
Publication Date: 09.11.2017 International Filing Date: 03.05.2017
IPC:
G01N 33/49 (2006.01) ,G01N 21/63 (2006.01)
G PHYSICS
01
MEASURING; TESTING
N
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33
Investigating or analysing materials by specific methods not covered by groups G01N1/-G01N31/131
48
Biological material, e.g. blood, urine; Haemocytometers
483
Physical analysis of biological material
487
of liquid biological material
49
blood
G PHYSICS
01
MEASURING; TESTING
N
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
21
Investigating or analysing materials by the use of optical means, i.e. using infra-red, visible, or ultra-violet light
62
Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
63
optically excited
Applicants: LABTHROUGHPUT LLC[US/US]; 8 Smolley Drive Monsey, NY 10952, US
Inventors: ZELMANOVIC, David; US
ROCHE, John; US
Agent: VOLK, Brian, R.; US
Priority Data:
62/331,82904.05.2016US
Title (EN) SYSTEM AND METHOD FOR DISTINGUISHING BLOOD COMPONENTS
(FR) SYSTÈME ET PROCÉDÉ POUR DISTINGUER DES COMPOSANTS SANGUINS
Abstract:
(EN) A method for measuring concentrations of blood cell components is provided. The method comprises: obtaining a blood sample from a subject, the blood sample comprising red blood cells (RBCs), white blood cells (WBCs), and platelets (PLTs); mixing the blood sample with a non-lysing aqueous solution to form a sample mixture comprising a predetermined tonicity; passing the sample mixture through a flow cell; emitting light towards the flow cell; measuring an amount of light absorbed by the RBCs; measuring an amount of light scattered by WBCs, and PLTs; determining a concentration of each of the RBCs, WBCs, and PLTs present in the sample mixture from the measured amount of light absorbed by the RBCs and scattered by the WBCs and PLTs.
(FR) La présente invention concerne un procédé de mesure de concentrations de composants de cellules sanguines. Le procédé comprend : l'obtention d'un échantillon de sang d'un sujet, l'échantillon de sang comprenant des globules rouges (RBC), des globules blancs (WBC) et des plaquettes (PLT) ; le mélange de l'échantillon de sang avec une solution aqueuse non lytique pour former un mélange d'échantillon comprenant une tonicité prédéterminée ; faire passer le mélange d'échantillon à travers une cellule à circulation ; émettre de la lumière vers la cellule à circulation ; la mesure d’une quantité de lumière absorbée par les RBC ; la mesure d’une quantité de lumière diffusée par les WBC et PLT ; la détermination d’une concentration de chacun des RBC, WBC et PLT présents dans le mélange d'échantillon à partir de la quantité mesurée de lumière absorbée par les RBC et diffusée par les WBC et les PLT.
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)